Recombinant Human Thrombopoietin / THPO Protein – Discontinued

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SKU: QP5228
Species: Human
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 90 as determined by SDS-PAGE.
Length (Amino Acids): 175

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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Bioactivity (test results eg. IU/ml):


SKU: QP5228-1mg
Recombinant Human Thrombopoietin / THPO Protein (Animal Free) General Information
Alternate Names
Thrombopoietin, THPO, MPLLG, MKCSF, THCYT1, TPO, MGDF, ML
Curated Database and Bioinformatic Data
Gene Symbol THPO
Entrez Gene ID 7066
Ensemble Gene ID ENSG00000090534
RefSeq Protein Accession(s) NP_000451.1
RefSeq mRNA Accession(s) NM_000460.3, NM_001177597.2, NM_001177598.2, NM_001289997.1, NM_001289998.1, NM_001290003.1, NM_001290022.1, NM_001290026.1, NM_001290027.1, NM_001290028.1
UniProt ID(s) P40225
UniGene ID(s) Hs.1166
HGNC ID(s) HGNC:11795
COSMIC ID Link(s) THPO
KEGG Gene ID(s) hsa:7066
PharmGKB ID(s) PA36506
General Description of Recombinant Human Thrombopoietin / THPO Protein (Animal Free).
Thrombopoietin (TPO) is a growth factor that is produced by liver and kidney tissues. TPO binds the TPO receptor (CD110) to promote megakaryocyte maturation, differentiation, and the production of platelets.

Human Thrombopoietin / THPO Bioactive Protein - Discontinued

This product has been discontinued because of cost to manufacture.
Product Type: Bioactive Protein
Recombinant Thrombopoietin / THPO based upon sequence from: Human
Host: QP5228 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5228.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 5 ng/mL in the MO7e cell proliferaiton assay. The bioactivity acceptance criteria is set at 2 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MSPAPPACDL RVLSKLLRDS HVLHSRLSQC PEVHPLPTPV LLPAVDFSLG EWKTQMEETK AQDILGAVTL LLEGVMAARG QLGPTCLSSL LGQLSGQVRL LLGALQSLLG TQLPPQGRTT AHKDPNAIFL SFQHLLRGKV RFLMLVGGST LCVRRAPPTT AVPSRTSLVL TLNEL
Purity: Greater than 90 as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Thrombopoietin / THPO Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 10 mM sodium phosphate, pH 7.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Thrombopoietin / THPO Protein - Discontinued