Recombinant Mouse CD40L / CD154 / TNFSF5 Protein

$ 69.00 – $ 2,798.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5411
Species: Mouse
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 149

Product Number	Description	Price
QP5411-5ug	Size: 5 ug, Tag: Untagged (Native Protein)	$ 69.00
QP5411-25ug	Size: 25 ug, Tag: Untagged (Native Protein)	$ 169.00
QP5411-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 419.00
QP5411-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 1,718.00
QP5411-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 2,798.00

Shipping Information

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5411-25ug

Recombinant Mouse CD40L / CD154 / TNFSF5 Protein General Information
Alternate Names
CD40L, CD154, TNFSF5, CD154, IGM, Ly-62, TRAP, Tnlg8b, HIGM1, CD40-L, Cd40l, Ly62, T-BAM, IMD3, Tnfsf5, gp39
Curated Database and Bioinformatic Data
Gene Symbol	CD40LG
Entrez Gene ID	21947
Ensemble Gene ID	ENSMUSG00000031132
RefSeq Protein Accession(s)	NP_035746.2
RefSeq mRNA Accession(s)	NM_011616.2
UniProt ID(s)	P27548
UniGene ID(s)	Mm.4861
COSMIC ID Link(s)	CD40LG
KEGG Gene ID(s)	mmu:21947
General Description of Recombinant Mouse CD40L / CD154 / TNFSF5 Protein .
CD40 Ligand (CD40L), or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells, monocytes, basophils, eosinophils, platelets, dendritic cells, and endothelial cells. CD40L binds and activates the CD40 receptor on antigen-presenting cells. CD40L stimulates B cell proliferation, immunoglobulin class switching, and antibody secretion. CD40L also induces cytokine production and tumoricidal activity in peripheral blood monocytes. CD40L is a co-stimulator of activated T cell proliferation and inflammatory protein production.

Mouse CD40L / CD154 / TNFSF5 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant CD40L / CD154 / TNFSF5 based upon sequence from: Mouse

Host: QP5411 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5411.

Bioactivity Data: Recombinant Mouse CD40L / CD154 / TNFSF5 induced IL-8 production in human PBMCs detected via ELISA (typical ED50 is 1-10 ng/ml). Activity is also measured in HEK-Blue&trade. CD40L validation criteria in this assay is an ED50 of less than 50 ng/ml.

Monomer or Dimer: Monomer

Amino Acid Sequence: MQRGDEDPQI AAHVVSEANS NAASVLQWAK KGYYTMKSNL VMLENGKQLT VKREGLYYVY TQVTFCSNRE PSSQRPFIVG LWLKPSSGSE RILLKAANTH SSSQLCEQQS VHLGGVFELQ AGASVFVNVT EASQVIHRVG FSSFGLLKL

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Mouse CD40L / CD154 / TNFSF5 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: 10 mM sodium phosphate, 50 mM arginine, pH7.5

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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