Recombinant Mouse IL-11 / interleukin 11 Protein

$ 69.00$ 4,898.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5472
Species: Mouse
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 179

Size
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Shipping Information
1-2 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP5472-2ug
Recombinant Mouse IL-11 / interleukin 11 Protein General Information
Alternate Names
IL-11, interleukin 11, AGIF, IL-11
Curated Database and Bioinformatic Data
Gene SymbolIL11
Entrez Gene ID16156
Ensemble Gene IDENSMUSG00000004371
RefSeq Protein Accession(s)NP_032376.1
RefSeq mRNA Accession(s)NM_008350.4
UniProt ID(s)P47873
UniGene ID(s)Mm.35814
COSMIC ID Link(s)IL11
KEGG Gene ID(s)mmu:16156
General Description of Recombinant Mouse IL-11 / interleukin 11 Protein.
Interleukin 11 (IL-11) is a member of the gp130 family of cytokines. IL-11 functions to promote hematopoietic stem cell proliferation and megakaryocyte differentiation. In non-hematopoietic cell populations, IL-11 stimulates acute-phase proteins, modulates the development of immunoglobulin-producing B cells, and regulates bone turnover. IL-11 binds the IL-11Ralpha (IL-11R?) receptor to activate JAK downstream signaling.

Mouse IL-11 / interleukin 11 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL-11 / interleukin 11 based upon sequence from Mouse
Host: QP5472 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5472.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 2.5 ng/mL in the T11 cell proliferation assay. The bioactivity acceptance criteria is set at 4 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MPGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDH SLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLK TLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGS IRAAHAILGG LHLTLDWAVR GLLLLKTRL
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse IL-11 / interleukin 11 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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