Recombinant Mouse IL21 / Interleukin 21 Protein

$ 69.00$ 4,898.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP1484
Species: Mouse
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 130

Size
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Shipping Information
1-2 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP1484-2 ug
Recombinant Mouse IL21 / Interleukin 21 Protein General Information
Alternate Names
IL21, Interleukin 21, IL-21
Curated Database and Bioinformatic Data
Gene SymbolIL21
Entrez Gene ID60505
Ensemble Gene IDENSMUSG00000027718
RefSeq Protein Accession(s)NP_068554.1
RefSeq mRNA Accession(s)NM_021782.3
UniProt ID(s)Q9ES17
UniGene ID(s)Mm.157689
COSMIC ID Link(s)IL21
KEGG Gene ID(s)mmu:60505
General Description of Recombinant Mouse IL21 / Interleukin 21 Protein.
Interleukin 21 (IL-21) is a member of the common-gamma chain family of cytokines that are involved in immunoregulation. IL-21 is normally expressed by activated CD4+ T cells. The IL-21 receptor (IL-21R) activates the JAK/STAT signaling pathway and is expressed on T, B, and natural killer (NK) cells. Within the B cell lineage, IL-21 is a switch factor regulating IgG1 and IgG3 antibody production. IL-21 also cooperates with interleukin 4 (IL-4) for the production of multiple antibody classes in B cells. IL-21 has pleiotropic effects on the proliferation, differentiation, and effector functions of B, T, NK, and dendritic cells.

Mouse IL21 / Interleukin 21 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL21 / Interleukin 21 based upon sequence from Mouse
Host: QP1484 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1484.
Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 10 ng/mL in the Mouse thymocyte proliferation assay. The bioactivity acceptance criteria is set at 1 x 10^5 units/mg.
Monomer or Dimer: Monomer
Amino Acid Sequence: MHKSSPQGPD RLLIRLRHLI DIVEQLKIYE NDLDPELLSA PQDVKGHCEH AAFACFQKAK LKPSNPGNNK TFIIDLVAQL RRRLPARRGG KKQKHIAKCP SCDSYEKRTP KEFLERLKWL LQKMIHQHLS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Mouse IL21 / Interleukin 21 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: 20 mM sodium bicarbonate, pH 8.5
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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