Recombinant Mouse LIF Protein

$ 88.00 – $ 3,188.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5442
Species: Mouse
Applications: Bioactive
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids): 181

Product Number	Description	Price
QP5442-5ug	Size: 5 ug, Tag: Untagged (Native Protein)	$ 79.00
QP5442-20ug	Size: 20 ug, Tag: Untagged (Native Protein)	$ 189.00
QP5442-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 589.00
QP5442-500ug	Size: 500 ug, Tag: Untagged (Native Protein)	$ 1,748.00
QP5442-1mg	Size: 1 mg, Tag: Untagged (Native Protein)	$ 2,848.00

Shipping Information

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5442-20ug

Recombinant Mouse LIF Protein (Animal Free) General Information
Alternate Names
LIF, MLPLI, CDF, DIA, HILDA
Curated Database and Bioinformatic Data
Gene Symbol	LIF
Entrez Gene ID	16878
Ensemble Gene ID	ENSMUSG00000034394
RefSeq Protein Accession(s)	NP_001034626.1
RefSeq mRNA Accession(s)	NM_001039537.2, NM_008501.2, XM_006514542.3, XM_006514543.3
UniProt ID(s)	P09056
UniGene ID(s)	Mm.4964
COSMIC ID Link(s)	LIF
KEGG Gene ID(s)	mmu:16878
General Description of Recombinant Mouse LIF Protein (Animal Free).
Mouse leukemia inhibitory factor (LIF) is a member of the interleukin 6 (IL-6) family that is made by a variety of adult and embryonic tissues. LIF signals through the glycoprotein 130 (gp130)/LIF receptor (LIFR) heterodimer to activate STAT3 and MAPK signaling. LIF functions during hematopoietic differentiation, neuronal cell differentiation, kidney development, and inflammatory processes. The application of mouse LIF to long-term culture systems promotes mouse embryonic stem (ES) cell self-renewal and pluripotency, similar to the functional activity of bFGF (FGF2) in human ES cell culture systems.

Mouse LIF Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant LIF based upon sequence from: Mouse

Host: QP5442 protein expressed in E. coli.

Tag: Untagged

Recommended Applications: Bioactive

Application Notes: Please contact us for application specific information for QP5442.

Bioactivity Data: BioActivity: Shows bioactivity at a concentration of 1 ng/mL in the Inhibit M1 cell proliferation assay. The bioactivity acceptance criteria is set at 1 x 10^6 units/mg.

Monomer or Dimer: Monomer

Amino Acid Sequence: MSPLPITPVN ATCAIRHPCH GNLMNQIKNQ LAQLNGSANA LFISYYTAQG EPFPNNVEKL CAPNMTDFPS FHGNGTEKTK LVELYRMVAY LSASLTNITR DQKVLNPTAV SLQVKLNATI DVMRGLLSNV LCRLCNKYRV GHVDVPPVPD HSDKEAFQRK KLGCQLLGTY KQVISVVVQA F

Purity: Greater than 95% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Mouse LIF Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.

Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA

Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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