Recombinant Human Fibroblast growth factor 23 Protein

$ 108.00 – $ 2,088.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP10385
Species: Human
Available Tags: Untagged
Host: E. coli
Purity: Greater than 95% as determined by SDS-PAGE and HPLC.
Length (Amino Acids): 227

Product Number	Description	Price
QP10385-ec-5ug	Size: 5 ug, Tag: Untagged (Native Protein)	$ 98.00
QP10385-ec-20ug	Size: 20 ug, Tag: Untagged (Native Protein)	$ 248.00
QP10385-ec-100ug	Size: 100 ug, Tag: Untagged (Native Protein)	$ 1,058.00
QP10385-ec-250ug	Size: 250 ug, Tag: Untagged (Native Protein)	$ 1,858.00

Shipping Information

7-10 days

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP10385-ec-5ug

Recombinant Human Fibroblast growth factor 23 Protein General Information
Alternate Names
HPDR2; PHPTC; ADHR; FGFN; HYPF
Curated Database and Bioinformatic Data
Gene Symbol	FGF23
Entrez Gene ID	8074
Ensemble Gene ID	ENSG00000118972
RefSeq Protein Accession(s)	NP_065689.1
RefSeq mRNA Accession(s)	NM_020638.2
UniProt ID(s)	Q9GZV9
HGNC ID(s)	HGNC:3680
COSMIC ID Link(s)	FGF23
KEGG Gene ID(s)	hsa:8074
PharmGKB ID(s)	PA28119
General Description of Recombinant Human Fibroblast growth factor 23 Protein.
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

Human Fibroblast growth factor 23 Bioactive Protein Product Attributes

Product Type: Bioactive Protein

Recombinant Fibroblast growth factor 23 based upon sequence from: Human

Host: QP10385 protein expressed in E. coli.

Tag: Untagged

Protein Construction: A DNA sequence encoding the Human Fibroblast growth factor 23, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP10385.

Bioactivity Data: Equivalent or superior bioactivity to competitors. Data available upon request. The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 ug/ml, corresponding to a specific activity of > 2.0 Ã 103 IU/mg in the presence of 0.3 ug/ml of rMuKlotho and 10 ug/ml of heparin.

Full Length? Partial (see sequence information for more details).

Amino Acid Sequence: (M)YPNASPLLGS SWGGLIHLYT ATARNSYHLQ IHKNGHVDGA PHQTIYSALM IRSEDAGFVV ITGVMSRRYL CMDFRGNIFG SHYFDPENCR FQHQTLENGY DVYHSPQYHF LVSLGRAKRA FLPGMNPPPY SQFLSRRNEI PLIHFNTPIP RRHTRSAEDD SERDPLNVLK PRARMTPAPA SCSQELPSAE DNSPMASDPL GVVRGGRVNT HAGGTGPEGC RPFAKFI

Purity: Greater than 95% as determined by SDS-PAGE and HPLC.

Reconstitution Instructions:

Concentration of Human Fibroblast growth factor 23 Protein: Lyophilized. Concentration determined by reconstitution volume.

Endotoxin Levels: Less than 1.0 EU/ug as determined by LAL method.

Buffer: 0.2 um filtered PBS, pH 7.4, lyophilized

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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