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Recombinant Human EPOR Protein

$ 89.00$ 1,200.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10591
Species: Human
Applications: Bioactive
Available Tags: His
Available Hosts: Insect
Purity: Greater than 95.0% as determined by analysis by SDS-PAGE.
Length (Amino Acids):

Size
Tag Clear selection
Shipping Information
1-3 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP10591-2ug
Recombinant Human EPOR General Information
EPOR  protein 3D structural model from Catalog of Somatic Mutations in Cancer originally published in the paper COSMIC: somatic cancer genetics at high-resolution
Alternate Names
EPO-R, EPOR, Erythropoietin Receptor.
Molecular Weight
25.6 kDa
Chromosomal Location
p13.2 on chromosome 19
Curated Database and Bioinformatic Data
Gene SymbolEPOR
Entrez Gene ID2057
UniProt ID(s)P19235
COSMIC ID Link(s)EPOR
KEGG Gene ID(s)hsa:2057
General Description of Recombinant Human EPOR.
EPOR produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 232 amino acids (25-250AA ) and having a molecular mass of 25.6kDa (Molecular size on SDS-PAGE will appear at approximately 28-40kDa). EPOR is expressed with a 6 amino acid His-tag at C-Terminus and purified by using an optimized multi-step FPLC method for maximum separation from contaminants.

Human EPOR Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant EPOR based upon sequence from Human
Host: QP10591 protein expressed in Insect.
Available Tags: His
Protein Construction: A cDNA sequence encoding the sequence of EPOR was constructred and used to recombinantly synthesize the protein.
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP10591.
Bioactivity Data: Measured by its ability to inhibit EPO dependent proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect less or equal to 70ng/ml.
Amino Acid Sequence: APPPNLPDPK FESKAALLAA RGPEELLCFT ERLEDLVCFW EEAASAGVGP GNYSFSYQLE DEPWKLCRLH QAPTARGAVR FWCSLPTADT SSFVPLELRV TAASGAPRYH RVIHINEVVL LDAPVGLVAR LADESGHVVL RWLPPPETPM TSHIRYEVDV SAGNGAGSVQ RVEILEGRTE CVLSNLRGRT RYTFAVRARM AEPSFGGFWS AWSEPVSLLT PSDLDPHHHH HH
Purity: Greater than 95.0% as determined by analysis by SDS-PAGE.
Reconstitution Instructions: |||
Endotoxin Levels:
Buffer: EPOR protein solution (0.5 mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10% glycerol.
Storage Conditions: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Physical Appearance: Sterile Filtered clear solution.

Limitations and Performance Guarantee

enQuire Bio's products are guaranteed and approved for RESEARCH USE ONLY or manufacturing purposes. This product may not be used as a pharmaceutical agent, or other product intended for human consumption without meeting additional regulatory requirements. This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human EPOR Protein