PDF DatasheetHuman CCL18 / PARC / MIP4 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL18 / PARC / MIP4 based upon sequence from: Human
Host: QP5260 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5260.
Bioactivity Data: Human CCL18 / PARC / MIP4 induces primary human T cell chemotaxis.
Monomer or Dimer: Monomer
Amino Acid Sequence: AQVGTNKELC CLVYTSWQIP QKFLVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CCL18 / PARC / MIP4 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CCL18 / PARC / MIP4 Protein General Information | |
|---|---|
| Alternate Names | |
| CCL18, PARC, MIP4, CKb7, MIP-4, DCCK1, PARC, DC-CK1, SCYA18, AMAC1, AMAC-1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL18 |
| Entrez Gene ID | 6362 |
| Ensemble Gene ID | ENSG00000278167 |
| RefSeq Protein Accession(s) | NP_002979.1 |
| RefSeq mRNA Accession(s) | NM_002988.3 |
| UniProt ID(s) | P55774 |
| UniGene ID(s) | Hs.143961 |
| HGNC ID(s) | HGNC:10616 |
| KEGG Gene ID(s) | hsa:6362 |
| PharmGKB ID(s) | PA35549 |
| General Description of Recombinant Human CCL18 / PARC / MIP4 Protein . | |
| Macrophage inflammatory protein-4 (MIP-4), also called CCL18, is a chemokine expressed in the lymph nodes, lungs, placenta, and bone marrow. MIP-4 receptors include the chemokine receptor 8 (CCR8), the G protein-coupled receptor 30 (GPR30), and the phosphatidylinositol transfer protein membrane-associate 3 (PITPNM3). MIP-4 acts as a chemoattractant for naive T cells, CD4+ T cells, CD8+ T cells, and nonactivated lymphocytes. Further, MIP-4 promotes breast cancer metastasis and attenuates the activation of acute lymphocytic leukemia B cells. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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