PDF DatasheetHuman CCL5 / RANTES Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL5 / RANTES based upon sequence from: Human
Host: QP5261 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5261.
Bioactivity Data: BioActivity: Shows bioactivity in the THP-1 chemotaxis assay.
Monomer or Dimer: Monomer
Amino Acid Sequence: SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CCL5 / RANTES Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CCL5 / RANTES Protein General Information | |
|---|---|
| Alternate Names | |
| CCL5, RANTES, SISd, TCP228, D17S136E, RANTES, SCYA5, SIS-delta, eoCP | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL5 |
| Entrez Gene ID | 6352 |
| Ensemble Gene ID | ENSG00000271503 |
| RefSeq Protein Accession(s) | NP_002976.2 |
| RefSeq mRNA Accession(s) | NM_002985.2 |
| UniProt ID(s) | P13501 |
| UniGene ID(s) | Hs.514821 |
| HGNC ID(s) | HGNC:10632 |
| KEGG Gene ID(s) | hsa:6352 |
| PharmGKB ID(s) | PA35564 |
| General Description of Recombinant Human CCL5 / RANTES Protein. | |
| Regulated upon activation, normal T cell expressed and secreted (RANTES), also called CCL5, is a chemokine produced by T cells three to five days after T cell activation. RANTES signals through G protein-coupled receptors CCR5, CCR3, CCR1, and through the human CMV-encoded viral receptor US28. RANTES functions to recruit immune cells to inflammatory sites. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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