SDS-PAGE separation of QP10060 followed by commassie total protein stain results in a primary band consistent with reported data for Cdc42 / Rac. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP10060 followed by commassie total protein stain results in a primary band consistent with reported data for Cdc42 / Rac. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Cdc42 / Rac Protein

$ 598.00$ 1,658.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10060
Species: Human
Available Tags: His
Host: Baculovirus
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 293

Product NumberDescriptionPrice
QP10060-ba-20ug Size: 20 ug, Tag: His $ 598.00
QP10060-ba-100ug Size: 100 ug, Tag: His $ 1,658.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10060-ba-20ug
Recombinant Human Cdc42 / Rac Protein General Information
Alternate Names
PAK7; p21 protein (Cdc42/Rac)-activated kinase
Curated Database and Bioinformatic Data
Gene SymbolPAK7
Entrez Gene ID57144
Ensemble Gene IDENSG00000101349
RefSeq Protein Accession(s)NP_065074.1
RefSeq mRNA Accession(s)NM_020341.3, NM_177990.2, XM_017027960.1, XM_017027961.1, XM_017027962.1, XM_017027963.1, XM_017027964.1, XM_017027965.1
UniProt ID(s)Q8TB93
UniGene ID(s)Hs.32539
HGNC ID(s)HGNC:15916
COSMIC ID Link(s)PAK7
KEGG Gene ID(s)hsa:57144
PharmGKB ID(s)PA32922
General Description of Recombinant Human Cdc42 / Rac Protein.
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.

Human Cdc42 / Rac Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Cdc42 / Rac based upon sequence from: Human
Host: QP10060 protein expressed in Baculovirus.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Cdc42/Rac, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10060.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - Gln293
Amino Acid Sequence: MFGKKKKKIE ISGPSNFEHR VHTGFDAQEQ KFTGLPQQWH SLLADTANRP KPMVDPSCIT PIQLAPMKTI VRGNKPCKET SINGLLEDFD NISVTRSNSL RKESPPTPDQ GASSHGPGHA EENGFITFSQ YSSESDTTAD YTTEKYREKS LYGDDLDPYY RGSHAAKQNG HVMKMKHGEA YYSEVKPLKS DFARFSADYH SHLDSLSKPS EYSDLKWEYQ RASSSSPLDY SFQFTPSRTA GTSGCSKESL AYSESEWGPS LDDYDRRPKS SYLNQTSPQP TMRQRSRSGS GLQ
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Cdc42 / Rac Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Cdc42 / Rac Protein

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