enQuire Bio » Products » Recombinant Protein » Recombinant Human Polypyrimidine tract-binding protein 1
SDS-PAGE separation of QP10096 followed by commassie total protein stain results in a primary band consistent with reported data for Polypyrimidine tract-binding protein 1. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP10096 followed by commassie total protein stain results in a primary band consistent with reported data for Polypyrimidine tract-binding protein 1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Polypyrimidine tract-binding protein 1

$ 658.00 – $ 1,848.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10096
Species: Human
Available Tags: Flag
Host: Mammal
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 557

Product NumberDescriptionPrice
QP10096-ma-20ug Size: 20 ug, Tag: FLAG $ 658.00
QP10096-ma-50ug Size: 50 ug, Tag: FLAG $ 1,318.00
QP10096-ma-100ug Size: 100 ug, Tag: FLAG $ 1,848.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10096-ma-20ug
Recombinant Human Polypyrimidine tract-binding protein 1 Protein General Information
Alternate Names
pPTB; PTB3; HNRNP-I; PTB; HNRNPI; PTB-T; PTB2; HNRPI; PTB-1; PTB4
Molecular Weight
Isoform 3
Curated Database and Bioinformatic Data
Gene SymbolPTBP1
Entrez Gene ID5725
Ensemble Gene IDENSG00000011304
RefSeq Protein Accession(s)NP_002810.1
RefSeq mRNA Accession(s)NM_002819.4, NM_031990.3, NM_031991.3
UniProt ID(s)P26599
UniGene ID(s)Hs.172550
HGNC ID(s)HGNC:9583
COSMIC ID Link(s)PTBP1
KEGG Gene ID(s)hsa:5725
PharmGKB ID(s)PA33934
General Description of Recombinant Human Polypyrimidine tract-binding protein 1 Protein.
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10.

Human Polypyrimidine tract-binding protein 1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Polypyrimidine tract-binding protein 1 based upon sequence from: Human
Isoform: Isoform 3
Host: QP10096 protein expressed in Mammal.
Tag: Flag
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Polypyrimidine tract-binding protein 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10096.
Bioactivity Data: Untested
Full Length? Full length of Isoform 3
Expression Region: Met1 - Ile557
Amino Acid Sequence: MDGIVPDIAV GTKRGSDELF STCVTNGPFI MSSNSASAAN GNDSKKFKGD SRSAGVPSRV IHIRKLPIDV TEGEVISLGL PFGKVTNLLM LKGKNQAFIE MNTEEAANTM VNYYTSVTPV LRGQPIYIQF SNHKELKTDS SPNQARAQAA LQAVNSVQSG NLALAASAAA VDAGMAMAGQ SPVLRIIVEN LFYPVTLDVL HQIFSKFGTV LKIITFTKNN QFQALLQYAD PVSAQHAKLS LDGQNIYNAC CTLRIDFSKL TSLNVKYNND KSRDYTRPDL PSGDSQPSLD QTMAAAFGAP GIISASPYAG AGFPPTFAIP QAAGLSVPNV HGALAPLAIP SAAAAAAAAG RIAIPGLAGA GNSVLLVSNL NPERVTPQSL FILFGVYGDV QRVKILFNKK ENALVQMADG NQAQLAMSHL NGHKLHGKPI RITLSKHQNV QLPREGQEDQ GLTKDYGNSP LHRFKKPGSK NFQNIFPPSA TLHLSNIPPS VSEEDLKVLF SSNGGVVKGF KFFQKDRKMA LIQMGSVEEA VQALIDLHNH DLGENHHLRV SFSKSTI
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Polypyrimidine tract-binding protein 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Polypyrimidine tract-binding protein 1

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