SDS-PAGE separation of QP10131 followed by commassie total protein stain results in a primary band consistent with reported data for Tripartite motif-containing protein 72. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP10131 followed by commassie total protein stain results in a primary band consistent with reported data for Tripartite motif-containing protein 72. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Tripartite motif-containing protein 72

$ 438.00$ 1,228.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10131
Species: Human
Available Tags: Flag
Host: Mammal
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 269

Product NumberDescriptionPrice
QP10131-ma-20ug Size: 20 ug, Tag: FLAG $ 438.00
QP10131-ma-100ug Size: 100 ug, Tag: FLAG $ 1,228.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP10131-ma-20ug
Recombinant Human Tripartite motif-containing protein 72 Protein General Information
Alternate Names
MG53
Curated Database and Bioinformatic Data
Gene SymbolTRIM72
Entrez Gene ID493829
Ensemble Gene IDENSG00000177238
RefSeq Protein Accession(s)NP_001008275.2
RefSeq mRNA Accession(s)NM_001008274.3
UniProt ID(s)Q6ZMU5
UniGene ID(s)Hs.661859
HGNC ID(s)HGNC:32671
COSMIC ID Link(s)TRIM72
KEGG Gene ID(s)hsa:493829
PharmGKB ID(s)PA144596247
General Description of Recombinant Human Tripartite motif-containing protein 72 Protein.
Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca2+-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles

Human Tripartite motif-containing protein 72 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Tripartite motif-containing protein 72 based upon sequence from: Human
Host: QP10131 protein expressed in Mammal.
Tag: Flag
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Tripartite motif-containing protein 72, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP10131.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - Ser269
Amino Acid Sequence: MSAAPGLLHQ ELSCPLCLQL FDAPVTAECG HSFCRACLGR VAGEPAADGT VLCPCCQAPT RPQALSTNLQ LARLVEGLAQ VPQGHCEEHL DPLSIYCEQD RALVCGVCAS LGSHRGHRLL PAAEAHARLK TQLPQQKLQL QEACMRKEKS VAVLEHQLVE VEETVRQFRG AVGEQLGKMR VFLAALEGSL DREAERVRGE AGVALRRELG SLNSYLEQLR QMEKVLEEVA DKPQTEFLMK YCLVTSRLQK ILAESPPPAR LDIQLPIIS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Tripartite motif-containing protein 72 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Tripartite motif-containing protein 72

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