PDF DatasheetHuman Amino-terminal enhancer of split Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Amino-terminal enhancer of split based upon sequence from Human
Isoform: Isoform 2
Host: QP5618 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Amino-terminal enhancer of split, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5618.
Bioactivity Data: Untested
Full Length? Full Length of Isoform 2
Expression Region: Met1 – Asp264
Amino Acid Sequence: MCHKNGFPQE GGITAAFLQK RKLRLSKNHR PARAKVTEHV RGTRPGRATA GPAASTRAAG SLFFDRWGNR GPAGCRGSSH LPQQLKFTTS DSCDRIKDEF QLLQAQYHSL KLECDKLASE KSEMQRHYVM YYEMSYGLNI EMHKQAEIVK RLNGICAQVL PYLSQEHQQQ VLGAIERAKQ VTAPELNSII RQQLQAHQLS QLQALALPLT PLPVGLQPPS LPAVSAGTGL LSLSALGSQA HLSKEDKNGH DGDTHQEDDG EKSD
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Amino-terminal enhancer of split Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Amino-terminal enhancer of split Protein General Information | |
|---|---|
| Alternate Names | |
| GRG5, Grg-5, ESP1, TLE5, AES-1, AES-2, GRG | |
| Molecular Weight | |
| Isoform 2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | AES |
| Entrez Gene ID | 166 |
| Ensemble Gene ID | ENSG00000104964 |
| RefSeq Protein Accession(s) | NP_001121.2 |
| RefSeq mRNA Accession(s) | NM_001130.5, NM_198969.1, NM_198970.1 |
| UniProt ID(s) | Q08117 |
| UniGene ID(s) | Hs.515053 |
| HGNC ID(s) | HGNC:307 |
| COSMIC ID Link(s) | AES |
| KEGG Gene ID(s) | hsa:166 |
| PharmGKB ID(s) | PA24606 |
| General Description of Recombinant Human Amino-terminal enhancer of split Protein. | |
| Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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