SDS-PAGE separation of QP5639 followed by commassie total protein stain results in a primary band consistent with reported data for AKR1C4. These data demonstrate Greater than 80% as determined by SDS-PAGE.
SDS-PAGE separation of QP5639 followed by commassie total protein stain results in a primary band consistent with reported data for AKR1C4. These data demonstrate Greater than 80% as determined by SDS-PAGE.

Recombinant Human AKR1C4 Protein

$ 398.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5639
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 324

Product NumberDescriptionPrice
QP5639-ec-100ug Size: 100 ug, Tag: GST $ 398.00
QP5639-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5639-ec-10ug
Recombinant Human AKR1C4 Protein General Information
Alternate Names
AKR1C4, CDR, DD4, CHDR, 3-alpha-HSD, C11, HAKRA, DD-4
Curated Database and Bioinformatic Data
Gene SymbolAKR1C4
Entrez Gene ID1109
Ensemble Gene IDENSG00000198610
RefSeq Protein Accession(s)NP_001809.3
RefSeq mRNA Accession(s)NM_001818.3
UniProt ID(s)P17516
UniGene ID(s)Hs.567245
HGNC ID(s)HGNC:387
COSMIC ID Link(s)AKR1C4
KEGG Gene ID(s)hsa:1109
PharmGKB ID(s)PA24680
General Description of Recombinant Human AKR1C4 Protein.
Catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol (3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone (kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.

Human AKR1C4 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant AKR1C4 based upon sequence from Human
Host: QP5639 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) AKR1C4, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5639.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MDPKYQRVEL NDGHFMPVLG FGTYAPPEVP RNRAVEVTKL AIEAGFRHID SAYLYNNEEQ VGLAIRSKIA DGSVKREDIF YTSKLWCTFF QPQMVQPALE SSLKKLQLDY VDLYLLHFPM ALKPGETPLP KDENGKVIFD TVDLSATWEV MEKCKDAGLA KSIGVSNFNC RQLEMILNKP GLKYKPVCNQ VECHPYLNQS KLLDFCKSKD IVLVAHSALG TQRHKLWVDP NSPVLLEDPV LCALAKKHKQ TPALIALRYQ LQRGVVVLAK SYNEQRIREN IQVFEFQLTS EDMKVLDGLN RNYRYVVMDF LMDHPDYPFS DEY
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human AKR1C4 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human AKR1C4 Protein

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