Recombinant Human Caspase-14 / CASP14 Protein

$ 88.00$ 1,618.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5761
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 88

Product NumberDescriptionPrice
QP5761-ec-10ug Size: 10 ug, Tag: GST $ 88.00
QP5761-ec-50ug Size: 50 ug, Tag: GST $ 218.00
QP5761-ec-100ug Size: 100 ug, Tag: GST $ 348.00
QP5761-ec-200ug Size: 200 ug, Tag: GST $ 568.00
QP5761-ec-500ug Size: 500 ug, Tag: GST $ 988.00
QP5761-ec-1mg Size: 1 mg, Tag: GST $ 1,618.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:


Bioactivity (test results eg. IU/ml):

SKU: QP5761-ec-10ug
Recombinant Human Caspase-14 / CASP14 Protein General Information
Alternate Names
Caspase-14, CASP14
Curated Database and Bioinformatic Data
Gene SymbolCASP14
Entrez Gene ID23581
Ensemble Gene IDENSG00000105141
RefSeq Protein Accession(s)NP_036246.1
RefSeq mRNA Accession(s)NM_012114.2
UniProt ID(s)P31944
UniGene ID(s)Hs.466057
KEGG Gene ID(s)hsa:23581
PharmGKB ID(s)PA26085
General Description of Recombinant Human Caspase-14 / CASP14 Protein.
Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum . Ses to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin . In vitro has a preference for the substate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF . Involved in processing of prosaposin in the epidermis . May be involved in retinal pigment epithelium cell barrier function . Involved in DNA degradation in differentiated keratinocytes probably by cleaving DFFA/ICAD leading to liberation of DFFB/CAD .

Human Caspase-14 / CASP14 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Caspase-14 / CASP14 based upon sequence from Human
Host: QP5761 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Caspase-14 / CASP14, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5761.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Lys153 - Tyr240
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Caspase-14 / CASP14 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Caspase-14 / CASP14 Protein