SDS-PAGE separation of QP5769 followed by commassie total protein stain results in a primary band consistent with reported data for Chromobox protein homolog 7. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP5769 followed by commassie total protein stain results in a primary band consistent with reported data for Chromobox protein homolog 7. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Chromobox protein homolog 7 Protein

$ 148.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5769
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: E.coli, Yeast.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 251

Product NumberDescriptionPrice
QP5769-ec-10ug Size: 10 ug, Tag: His $ 148.00
QP5769-ec-100ug Size: 100 ug, Tag: His $ 398.00
QP5769-ec-1mg Size: 1 mg, Tag: His $ 1,728.00
QP5769-ye-100ug Size: 100 ug, Tag: His $ 468.00
QP5769-ye-500ug Size: 500 ug, Tag: His $ 1,298.00
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2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
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SKU: QP5769-ec-10ug
Recombinant Human Chromobox protein homolog 7 Protein General Information
Curated Database and Bioinformatic Data
Gene SymbolCBX7
Entrez Gene ID23492
Ensemble Gene IDENSG00000100307
RefSeq Protein Accession(s)NP_783640.1
RefSeq mRNA Accession(s)NM_175709.4
UniProt ID(s)O95931
UniGene ID(s)Hs.356416
HGNC ID(s)HGNC:1557
COSMIC ID Link(s)CBX7
KEGG Gene ID(s)hsa:23492
PharmGKB ID(s)PA26132
General Description of Recombinant Human Chromobox protein homolog 7 Protein.
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin rodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.

Human Chromobox protein homolog 7 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Chromobox protein homolog 7 based upon sequence from Human
Host: QP5769 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Chromobox protein homolog 7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5769.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Phe251
Amino Acid Sequence: MELSAIGEQV FAVESIRKKR VRKGKVEYLV KWKGWPPKYS TWEPEEHILD PRLVMAYEEK EERDRASGYR KRGPKPKRLL LQRLYSMDLR SSHKAKGKEK LCFSLTCPLG SGSPEGVVKA GAPELVDKGP LVPTLPFPLR KPRKAHKYLR LSRKKFPPRG PNLESHSHRR ELFLQEPPAP DVLQAAGEWE PAAQPPEEEA DADLAEGPPP WTPALPSSEV TVTDITANSI TVTFREAQAA EGFFRDRSGK F
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Chromobox protein homolog 7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Chromobox protein homolog 7 Protein

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