Recombinant Macaque CD40L / CD154 / TNFSF5 Protein

$ 188.00 – $ 1,618.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP5786
Species: Macaque
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 218

Product Number	Description	Price
QP5786-ec-10ug	Size: 10 ug, Tag: His	$ 218.00
QP5786-ec-50ug	Size: 50 ug, Tag: His	$ 288.00
QP5786-ec-100ug	Size: 100 ug, Tag: His	$ 518.00
QP5786-ec-200ug	Size: 200 ug, Tag: His	$ 638.00
QP5786-ec-500ug	Size: 500 ug, Tag: His	$ 1,108.00
QP5786-ec-1mg	Size: 1 mg, Tag: His	$ 1,818.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP5786-ec-10ug

Recombinant Macaque CD40L / CD154 / TNFSF5 Protein General Information
Alternate Names
CD40L, CD154, TNFSF5, CD154, IGM, Ly-62, TRAP, Tnlg8b, HIGM1, CD40-L, Cd40l, Ly62, T-BAM, IMD3, Tnfsf5, gp39
Curated Database and Bioinformatic Data
Gene Symbol	CD40LG
Entrez Gene ID	574160
RefSeq Protein Accession(s)	NP_001028011.1
RefSeq mRNA Accession(s)	NM_001032839.1
UniProt ID(s)	P63304
UniGene ID(s)	Mmu.3581
COSMIC ID Link(s)	CD40LG
KEGG Gene ID(s)	mcc:574160
General Description of Recombinant Macaque CD40L / CD154 / TNFSF5 Protein.
Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching.

Macaque CD40L / CD154 / TNFSF5 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant CD40L / CD154 / TNFSF5 based upon sequence from Macaque

Host: QP5786 protein expressed in E. coli.

Tag: His

Protein Construction: A DNA sequence encoding the Macaca mulatta (Rhesus macaque) CD40L / CD154 / TNFSF5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP5786.

Bioactivity Data: Untested

Full Length? Extracellular Domain

Expression Region: Val44 - Leu261

Amino Acid Sequence: VYLHRRLDKI EDERNLHEDF VFMKTIQRCN TGERSLSLLN CEEIKSQFEG FVKDIMLNKE EKKKENSFEM QKGDQNPQIA AHVISEASSK TTSVLQWAEK GYYTMSNNLV TLENGKQLTV KRQGLYYIYA QVTFCSNREA SSQAPFIASL CLKSPGRFER ILLRAANTHS SAKPCGQQSI HLGGVFELQP GASVFVNVTD PSQVSHGTGF TSFGLLKL

Purity: Greater than 80% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Macaque CD40L / CD154 / TNFSF5 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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