SDS-PAGE separation of QP5807 followed by commassie total protein stain results in a primary band consistent with reported data for p21WAF1. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP5807 followed by commassie total protein stain results in a primary band consistent with reported data for p21WAF1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human p21WAF1 Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5807
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 163

Product NumberDescriptionPrice
QP5807-ec-100ug Size: 100 ug, Tag: GST $ 398.00
QP5807-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5807-ec-10ug
Recombinant Human p21WAF1 Protein General Information
Alternate Names
p21WAF1, CIP1, CAP20, CDKN1, MDA-6, P21, SDI1, WAF1, p21CIP1
Curated Database and Bioinformatic Data
Gene SymbolCDKN1A
Entrez Gene ID1026
Ensemble Gene IDENSG00000124762
RefSeq Protein Accession(s)NP_000380.1
RefSeq mRNA Accession(s)NM_000389.4, NM_001220777.1, NM_001220778.1, NM_001291549.1, NM_078467.2
UniProt ID(s)P38936
UniGene ID(s)Hs.370771
HGNC ID(s)HGNC:1784
COSMIC ID Link(s)CDKN1A
KEGG Gene ID(s)hsa:1026
PharmGKB ID(s)PA104
General Description of Recombinant Human p21WAF1 Protein.
May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin-dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assbly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D-CDK4 complex.

Human p21WAF1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant p21WAF1 based upon sequence from Human
Host: QP5807 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) p21WAF1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5807.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ser2 - Pro164
Amino Acid Sequence: SEPAGDVRQN PCGSKACRRL FGPVDSEQLS RDCDALMAGC IQEARERWNF DFVTETPLEG DFAWERVRGL GLPKLYLPTG PRRGRDELGG GRRPGTSPAL LQGTAEEDHV DLSLSCTLVP RSGEQAEGSP GGPGDSQGRK RRQTSMTDFY HSKRRLIFSK RKP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human p21WAF1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human p21WAF1 Protein

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