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Recombinant Human CHI3L1 / YKL40 Protein

$ 398.00 – $ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5829
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: HIs-Myc
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 362

Product NumberDescriptionPrice
QP5829-ec-100ug Size: 100 ug, Tag: His-Myc $ 398.00
QP5829-ec-1mg Size: 1 mg, Tag: His-Myc $ 1,728.00
Shipping Information
1-2 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5829-ec-10ug
Recombinant Human CHI3L1 / YKL40 Protein General Information
Alternate Names
CHI3L1, YKL40, GP39, ASRT7, YYL-40, hCGP-39, CGP-39, YKL-40, YKL40, GP-39, HCGP-3P, HC-gp39
Curated Database and Bioinformatic Data
Gene SymbolCHI3L1
Entrez Gene ID1116
Ensemble Gene IDENSG00000133048
RefSeq Protein Accession(s)NP_001267.2
RefSeq mRNA Accession(s)NM_001276.2
UniProt ID(s)P36222
UniGene ID(s)Hs.382202
HGNC ID(s)HGNC:1932
COSMIC ID Link(s)CHI3L1
KEGG Gene ID(s)hsa:1116
PharmGKB ID(s)PA26463
General Description of Recombinant Human CHI3L1 / YKL40 Protein.
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.

Human CHI3L1 / YKL40 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant CHI3L1 / YKL40 based upon sequence from Human
Host: QP5829 protein expressed in E. coli.
Tag: HIs-Myc
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CHI3L1 / YKL40, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5829.
Bioactivity Data: Untested
Full Length? Full Length of Mature Protein
Expression Region: Tyr22 - Thr383
Amino Acid Sequence: YKLVCYYTSW SQYREGDGSC FPDALDRFLC THIIYSFANI SNDHIDTWEW NDVTLYGMLN TLKNRNPNLK TLLSVGGWNF GSQRFSKIAS NTQSRRTFIK SVPPFLRTHG FDGLDLAWLY PGRRDKQHFT TLIKEMKAEF IKEAQPGKKQ LLLSAALSAG KVTIDSSYDI AKISQHLDFI SIMTYDFHGA WRGTTGHHSP LFRGQEDASP DRFSNTDYAV GYMLRLGAPA SKLVMGIPTF GRSFTLASSE TGVGAPISGP GIPGRFTKEA GTLAYYEICD FLRGATVHRI LGQQVPYATK GNQWVGYDDQ ESVKSKVQYL KDRQLAGAMV WALDLDDFQG SFCGQDLRFP LTNAIKDALA AT
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CHI3L1 / YKL40 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human CHI3L1 / YKL40 Protein