enQuire Bio » Products » Recombinant Protein » Recombinant Human EIF3E Protein
Placeholder

Recombinant Human EIF3E Protein

$ 578.00 – $ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP5971
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 445

Product NumberDescriptionPrice
QP5971-ec-100ug Size: 100 ug, Tag: GST $ 578.00
QP5971-ec-1mg Size: 1 mg, Tag: GST $ 2,468.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP5971-ec-10ug
Recombinant Human EIF3E Protein General Information
Alternate Names
INT6, EIF3-P48, eIF3-p46, EIF3S6, Eukaryotic translation initiation factor 3 subunit
Curated Database and Bioinformatic Data
Gene SymbolEIF3E
Entrez Gene ID3646
Ensemble Gene IDENSG00000104408
RefSeq Protein Accession(s)NP_001559.1
RefSeq mRNA Accession(s)NM_001568.2
UniProt ID(s)P60228
UniGene ID(s)Hs.405590
HGNC ID(s)HGNC:3277
COSMIC ID Link(s)EIF3E
KEGG Gene ID(s)hsa:3646
PharmGKB ID(s)PA27705
General Description of Recombinant Human EIF3E Protein.
omponent of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis . The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation . The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression . Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway . May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.

Human EIF3E Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant EIF3E based upon sequence from Human
Host: QP5971 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) EIF3E, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP5971.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: AEYDLTTRIA HFLDRHLVFP LLEFLSVKEI YNEKELLQGK LDLLSDTNMV DFAMDVYKNL YSDDIPHALR EKRTTVVAQL KQLQAETEPI VKMFEDPETT RQMQSTRDGR MLFDYLADKH GFRQEYLDTL YRYAKFQYEC GNYSGAAEYL YFFRVLVPAT DRNALSSLWG KLASEILMQN WDAAMEDLTR LKETIDNNSV SSPLQSLQQR TWLIHWSLFV FFNHPKGRDN IIDLFLYQPQ YLNAIQTMCP HILRYLTTAV ITNKDVRKRR QVLKDLVKVI QQESYTYKDP ITEFVECLYV NFDFDGAQKK LRECESVLVN DFFLVACLED FIENARLFIF ETFCRIHQCI SINMLADKLN MTPEEAERWI VNLIRNARLD AKIDSKLGHV VMGNNAVSPY QQVIEKTKSL SFRSQMLAMN IEKKLNQNSR SEAPNWATQD SGFY
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human EIF3E Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.

Be the first to review “Recombinant Human EIF3E Protein”

Your email address will not be published. Required fields are marked *

Share a Protocol (View Reviewed Protocols Below)

Protocol Title

Materials

Methods

Notes

  protocol submission gif

Related Products

-
enQuire Bio, LLC   8420 S Continental Divide Rd, #202   Littleton, CO 80127
Chat: See lower right corner. | enquire@enquirebio.com | Fax: 1-720-897-3730
Customer Service Available M-F 8AM-6PM MST or 24/7 Via Email

Recombinant Human EIF3E Protein