PDF DatasheetHuman Neuronal calcium sensor 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Neuronal calcium sensor 1 based upon sequence from Human
Host: QP6056 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Neuronal calcium sensor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6056.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: GKSNSKLKPE VVEELTRKTY FTEKEVQQWY KGFIKDCPSG QLDAAGFQKI YKQFFPFGDP TKFATFVFNV FDENKDGRIE FSEFIQALSV TSRGTLDEKL RWAFKLYDLD NDGYITRNEM LDIVDAIYQM VGNTVELPEE ENTPEKRVDR IFAMMDKNAD GKLTLQEFQE GSKADPSIVQ ALSLYDGLV
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Neuronal calcium sensor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Neuronal calcium sensor 1 Protein General Information | |
|---|---|
| Alternate Names | |
| FLUP, FREQ | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | NCS1 |
| Entrez Gene ID | 23413 |
| Ensemble Gene ID | ENSG00000107130 |
| RefSeq Protein Accession(s) | NP_001122298.1 |
| RefSeq mRNA Accession(s) | NM_001128826.1, NM_014286.3 |
| UniProt ID(s) | P62166 |
| UniGene ID(s) | Hs.642946 |
| HGNC ID(s) | HGNC:3953 |
| COSMIC ID Link(s) | NCS1 |
| KEGG Gene ID(s) | hsa:23413 |
| PharmGKB ID(s) | PA28371 |
| General Description of Recombinant Human Neuronal calcium sensor 1 Protein. | |
| Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin. Stimulates PI4KB kinase activity. Involved in long-term synaptic plasticity through its interaction with PICK1. May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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