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Recombinant Human HSD11B1 Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6183
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 268

Product NumberDescriptionPrice
QP6183-ec-100ug Size: 100 ug, Tag: His-SUMO $ 398.00
QP6183-ec-1mg Size: 1 mg, Tag: His-SUMO $ 1,728.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6183-ec-10ug
Recombinant Human HSD11B1 Protein General Information
Alternate Names
HDL, CORTRD2, 11-beta-HSD1, HSD11B, HSD11, 11-DH, HSD11L, SDR26C1, Corticosteroid 11-beta-dehydrogenase isozyme
Curated Database and Bioinformatic Data
Gene SymbolHSD11B1
Entrez Gene ID3290
Ensemble Gene IDENSG00000117594
RefSeq Protein Accession(s)NP_001193670.1
RefSeq mRNA Accession(s)NM_001206741.1, NM_005525.3, NM_181755.2
UniProt ID(s)P28845
UniGene ID(s)Hs.195040
HGNC ID(s)HGNC:5208
COSMIC ID Link(s)HSD11B1
KEGG Gene ID(s)hsa:3290
PharmGKB ID(s)PA29476
General Description of Recombinant Human HSD11B1 Protein.
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol .

Human HSD11B1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant HSD11B1 based upon sequence from Human
Host: QP6183 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) HSD11B1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6183.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Glu25 - Lys292
Amino Acid Sequence: EEFRPEMLQG KKVIVTGASK GIGREMAYHL AKMGAHVVVT ARSKETLQKV VSHCLELGAA SAHYIAGTME DMTFAEQFVA QAGKLMGGLD MLILNHITNT SLNLFHDDIH HVRKSMEVNF LSYVVLTVAA LPMLKQSNGS IVVVSSLAGK VAYPMVAAYS ASKFALDGFF SSIRKEYSVS RVNVSITLCV LGLIDTETAM KAVSGIVHMQ AAPKEECALE IIKGGALRQE EVYYDSSLWT TLLIRNPCRK ILEFLYSTSY NMDRFINK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human HSD11B1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human HSD11B1 Protein