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SDS-PAGE separation of QP6355 followed by commassie total protein stain results in a primary band consistent with reported data for METAP2 / MAP2. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP6355 followed by commassie total protein stain results in a primary band consistent with reported data for METAP2 / MAP2. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human METAP2 / MAP2 Protein

$ 148.00 – $ 2,008.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6355
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST, His
Host: E.coli, Yeast.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 477

Product NumberDescriptionPrice
QP6355-ec-10ug Size: 10 ug, Tag: GST $ 148.00
QP6355-ec-50ug Size: 50 ug, Tag: GST $ 218.00
QP6355-ec-100ug Size: 100 ug, Tag: GST $ 398.00
QP6355-ec-200ug Size: 200 ug, Tag: GST $ 628.00
QP6355-ec-500ug Size: 500 ug, Tag: GST $ 1,098.00
QP6355-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
QP6355-ye-10ug Size: 10 ug, Tag: His $ 188.00
QP6355-ye-50ug Size: 50 ug, Tag: His $ 258.00
QP6355-ye-100ug Size: 100 ug, Tag: His $ 468.00
QP6355-ye-200ug Size: 200 ug, Tag: His $ 748.00
QP6355-ye-500ug Size: 500 ug, Tag: His $ 1,298.00
QP6355-ye-1mg Size: 1 mg, Tag: His $ 2,008.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6355-ec-10ug
Recombinant Human METAP2 / MAP2 Protein General Information
Alternate Names
METAP2, MAP2, A930035J23Rik, Amp2, AL024412, Mnpep, 4930584B20Rik, AU014659, p67eIF2, AI047573, p67
Curated Database and Bioinformatic Data
Gene SymbolMETAP2
Entrez Gene ID10988
Ensemble Gene IDENSG00000111142
RefSeq Protein Accession(s)NP_001304111.1
RefSeq mRNA Accession(s)NM_001317182.1, NM_001317183.1, NM_001330246.1, NM_006838.3
UniProt ID(s)P50579
UniGene ID(s)Hs.444986
HGNC ID(s)HGNC:16672
COSMIC ID Link(s)METAP2
KEGG Gene ID(s)hsa:10988
PharmGKB ID(s)PA30765
General Description of Recombinant Human METAP2 / MAP2 Protein.
Cotranslationally roves the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo.Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

Human METAP2 / MAP2 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant METAP2 / MAP2 based upon sequence from Human
Host: QP6355 protein expressed in E.coli, Yeast..
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) METAP2 / MAP2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6355.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Ala2 - Tyr478
Amino Acid Sequence: AGVEEVAASG SHLNGDLDPD DREEGAASTA EEAAKKKRRK KKKSKGPSAA GEQEPDKESG ASVDEVARQL ERSALEDKER DEDDEDGDGD GDGATGKKKK KKKKKRGPKV QTDPPSVPIC DLYPNGVFPK GQECEYPPTQ DGRTAAWRTT SEEKKALDQA SEEIWNDFRE AAEAHRQVRK YVMSWIKPGM TMIEICEKLE DCSRKLIKEN GLNAGLAFPT GCSLNNCAAH YTPNAGDTTV LQYDDICKID FGTHISGRII DCAFTVTFNP KYDTLLKAVK DATNTGIKCA GIDVRLCDVG EAIQEVMESY EVEIDGKTYQ VKPIRNLNGH SIGQYRIHAG KTVPIVKGGE ATRMEEGEVY AIETFGSTGK GVVHDDMECS HYMKNFDVGH VPIRLPRTKH LLNVINENFG TLAFCRRWLD RLGESKYLMA LKNLCDLGIV DPYPPLCDIK GSYTAQFEHT ILLRPTCKEV VSRGDDY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human METAP2 / MAP2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human METAP2 / MAP2 Protein

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