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SDS-PAGE separation of QP6428 followed by commassie total protein stain results in a primary band consistent with reported data for Nephrocystin-1. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP6428 followed by commassie total protein stain results in a primary band consistent with reported data for Nephrocystin-1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Nephrocystin-1 Protein

$ 398.00 – $ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6428
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 109

Product NumberDescriptionPrice
QP6428-ec-100ug Size: 100 ug, Tag: GST $ 398.00
QP6428-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
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2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
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SKU: QP6428-ec-10ug
Recombinant Human Nephrocystin-1 Protein General Information
Alternate Names
JBTS4, NPH1, SLSN1
Curated Database and Bioinformatic Data
Gene SymbolNPHP1
Entrez Gene ID4867
Ensemble Gene IDENSG00000144061
RefSeq Protein Accession(s)NP_000263.2
RefSeq mRNA Accession(s)NM_000272.3, NM_001128178.1, NM_001128179.1, NM_207181.2
UniProt ID(s)O15259
UniGene ID(s)Hs.280388
HGNC ID(s)HGNC:7905
COSMIC ID Link(s)NPHP1
KEGG Gene ID(s)hsa:4867
PharmGKB ID(s)PA31706
General Description of Recombinant Human Nephrocystin-1 Protein.
Together with BCAR1 it may play a role in the control of epithelial cell polarity. Involved in the organization of apical junctions in kidney cells together with NPHP4 and RPGRIP1L/NPHP8 . Does not se to be strictly required for ciliogenesis . Ses to help to recruit PTK2B/PYK2 to cell matrix adhesions, thereby initiating phosphorylation of PTK2B/PYK2 and PTK2B/PYK2-dependent signaling. May play a role in the regulation of intraflagellar transport (IFT) during cilia assbly. Required for normal retina development. In connecting photoreceptor cilia influences the movent of some IFT proteins such as IFT88 and WDR19. Involved in spermatogenesis .

Human Nephrocystin-1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Nephrocystin-1 based upon sequence from Human
Host: QP6428 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Nephrocystin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6428.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - Thr109
Amino Acid Sequence: MLARRQRDPL QALRRRNQEL KQQVDSLLSE SQLKEALEPN KRQHIYQRCI QLKQAIDENK NALQKLSKAD ESAPVANYNQ RKEEEHTLLD KLTQQLQGLA VTISRENIT
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Nephrocystin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Nephrocystin-1 Protein

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