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Recombinant Human CD155 / PVR Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6559
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 323

Product NumberDescriptionPrice
QP6559-ec-100ug Size: 100 ug, Tag: His-SUMO $ 448.00
QP6559-ec-1mg Size: 1 mg, Tag: His-SUMO $ 1,938.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6559-ec-10ug
Recombinant Human CD155 / PVR Protein General Information
Alternate Names
CD155, PVR, D7Ertd458e, 3830421F03Rik, mE4, Tage4, CD155, necl-5, PVS, HVED, Taa1
Curated Database and Bioinformatic Data
Gene SymbolPVR
Entrez Gene ID5817
Ensemble Gene IDENSG00000073008
RefSeq Protein Accession(s)NP_001129240.1
RefSeq mRNA Accession(s)NM_001135768.2, NM_001135769.2, NM_001135770.3, NM_006505.4
UniProt ID(s)P15151
UniGene ID(s)Hs.171844
HGNC ID(s)HGNC:9705
COSMIC ID Link(s)PVR
KEGG Gene ID(s)hsa:5817
PharmGKB ID(s)PA34050
General Description of Recombinant Human CD155 / PVR Protein.
Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological synapse between NK cell and target cell. This may trigger adhesion and secretion of lytic granules and IFN-gamma and activate cytoxicity of activated NK cells. May also promote NK cell-target cell modular exchange, and PVR transfer to the NK cell. This transfer is more important in some tumor cells expressing a lot of PVR, and may trigger fratricide NK cell activation, providing tumors with a mechanism of immunoevasion. Plays a role in mediating tumor cell invasion and migration.

Human CD155 / PVR Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant CD155 / PVR based upon sequence from Human
Host: QP6559 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) CD155 / PVR, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6559.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Trp21 - Asn343
Amino Acid Sequence: WPPPGTGDVV VQAPTQVPGF LGDSVTLPCY LQVPNMEVTH VSQLTWARHG ESGSMAVFHQ TQGPSYSESK RLEFVAARLG AELRNASLRM FGLRVEDEGN YTCLFVTFPQ GSRSVDIWLR VLAKPQNTAE VQKVQLTGEP VPMARCVSTG GRPPAQITWH SDLGGMPNTS QVPGFLSGTV TVTSLWILVP SSQVDGKNVT CKVEHESFEK PQLLTVNLTV YYPPEVSISG YDNNWYLGQN EATLTCDARS NPEPTGYNWS TTMGPLPPFA VAQGAQLLIR PVDKPINTTL ICNVTNALGA RQAELTVQVK EGPPSEHSGI SRN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human CD155 / PVR Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human CD155 / PVR Protein