SEQUEST analysis of LC MS/MS spectra obtained from a run with QP6564 identified a match between this protein and the spectra of a peptide sequence that matches a region of Glutaminyl cyclase / QPCT.

Additional SEQUEST analysis of the LC MS/MS spectra from QP6564 identified an additional between this protein and the spectra of another peptide sequence that matches a region of Glutaminyl cyclase / QPCT confirming successful recombinant synthesis.

Recombinant Human Glutaminyl cyclase / QPCT Protein

$ 398.00 – $ 1,728.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP6564
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 333

Product Number	Description	Price
QP6564-ec-100ug	Size: 100 ug, Tag: His-SUMO	$ 398.00
QP6564-ec-1mg	Size: 1 mg, Tag: His-SUMO	$ 1,728.00

Shipping Information

1-2 weeks

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Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP6564-ec-10ug

Recombinant Human Glutaminyl cyclase / QPCT Protein General Information
Alternate Names
Glutaminyl cyclase, QPCT, GCT, sQC, QC
Curated Database and Bioinformatic Data
Gene Symbol	QPCT
Entrez Gene ID	25797
Ensemble Gene ID	ENSG00000115828
RefSeq Protein Accession(s)	NP_036545.1
RefSeq mRNA Accession(s)	NM_012413.3
UniProt ID(s)	Q16769
UniGene ID(s)	Hs.79033
HGNC ID(s)	HGNC:9753
COSMIC ID Link(s)	QPCT
KEGG Gene ID(s)	hsa:25797
PharmGKB ID(s)	PA34095
General Description of Recombinant Human Glutaminyl cyclase / QPCT Protein.
Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-beta-amyloid. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides.

Human Glutaminyl cyclase / QPCT Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Glutaminyl cyclase / QPCT based upon sequence from Human

Host: QP6564 protein expressed in E. coli.

Tag: His-SUMO

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Glutaminyl cyclase / QPCT, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.

Application Notes: Please contact us for application specific information for QP6564.

Bioactivity Data: Untested

Full Length? Full Length

Expression Region: Val29 - Leu361

Amino Acid Sequence: VSPSASAWPE EKNYHQPAIL NSSALRQIAE GTSISEMWQN DLQPLLIERY PGSPGSYAAR QHIMQRIQRL QADWVLEIDT FLSQTPYGYR SFSNIISTLN PTAKRHLVLA CHYDSKYFSH WNNRVFVGAT DSAVPCAMML ELARALDKKL LSLKTVSDSK PDLSLQLIFF DGEEAFLHWS PQDSLYGSRH LAAKMASTPH PPGARGTSQL HGMDLLVLLD LIGAPNPTFP NFFPNSARWF ERLQAIEHEL HELGLLKDHS LEGRYFQNYS YGGVIQDDHI PFLRRGVPVL HLIPSPFPEV WHTMDDNEEN LDESTIDNLN KILQVFVLEY LHL

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.

Concentration of Human Glutaminyl cyclase / QPCT Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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