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Recombinant Human GTP-binding nuclear protein Ran Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6583
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 216

Product NumberDescriptionPrice
QP6583-ec-100ug Size: 100 ug, Tag: GST $ 448.00
QP6583-ec-1mg Size: 1 mg, Tag: GST $ 1,938.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6583-ec-10ug
Recombinant Human GTP-binding nuclear protein Ran Protein General Information
Alternate Names
ARA24, Gsp1, TC4
Curated Database and Bioinformatic Data
Gene SymbolRAN
Entrez Gene ID5901
Ensemble Gene IDENSG00000132341
RefSeq Protein Accession(s)NP_001287725.1
RefSeq mRNA Accession(s)NM_001300796.1, NM_001300797.1, NM_006325.4
UniProt ID(s)P62826
UniGene ID(s)Hs.10842
HGNC ID(s)HGNC:9846
COSMIC ID Link(s)RAN
KEGG Gene ID(s)hsa:5901
PharmGKB ID(s)PA34205
General Description of Recombinant Human GTP-binding nuclear protein Ran Protein.
GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs. Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis. Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensure the directionality of the transport.

Human GTP-binding nuclear protein Ran Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant GTP-binding nuclear protein Ran based upon sequence from Human
Host: QP6583 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GTP-binding nuclear protein Ran, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6583.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: AAQGEPQVQF KLVLVGDGGT GKTTFVKRHL TGEFEKKYVA TLGVEVHPLV FHTNRGPIKF NVWDTAGQEK FGGLRDGYYI QAQCAIIMFD VTSRVTYKNV PNWHRDLVRV CENIPIVLCG NKVDIKDRKV KAKSIVFHRK KNLQYYDISA KSNYNFEKPF LWLARKLIGD PNLEFVAMPA LAPPEVVMDP ALAAQYEHDL EVAQTTALPD EDDDL
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human GTP-binding nuclear protein Ran Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human GTP-binding nuclear protein Ran Protein