SDS-PAGE separation of QP6633 followed by commassie total protein stain results in a primary band consistent with reported data for Ryanodine receptor 1. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP6633 followed by commassie total protein stain results in a primary band consistent with reported data for Ryanodine receptor 1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Ryanodine receptor 1 Protein

$ 398.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6633
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 534

Product NumberDescriptionPrice
QP6633-ec-100ug Size: 100 ug, Tag: His $ 448.00
QP6633-ec-1mg Size: 1 mg, Tag: His $ 1,938.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP6633-ec-10ug
Recombinant Human Ryanodine receptor 1 Protein General Information
Alternate Names
RYDR, MHS, MHS1, RYR, PPP1R137, CCO, RYR-1, SKRR
Curated Database and Bioinformatic Data
Gene SymbolRYR1
Entrez Gene ID6261
Ensemble Gene IDENSG00000196218
RefSeq Protein Accession(s)NP_000531.2
RefSeq mRNA Accession(s)NM_000540.2, NM_001042723.1
UniProt ID(s)P21817
UniGene ID(s)Hs.466664
HGNC ID(s)HGNC:10483
COSMIC ID Link(s)RYR1
KEGG Gene ID(s)hsa:6261
PharmGKB ID(s)PA34896
General Description of Recombinant Human Ryanodine receptor 1 Protein.
Calcium channel that mediates the release of Ca2+ from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules. Repeated very high-level exercise increases the open probability of the channel and leads to Ca2+ leaking into the cytoplasm. Can also mediate the release of Ca2+ from intracellular stores in neurons, and may thereby promote prolonged Ca2+ signaling in the brain. Required for normal bryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during bryogenesis .

Human Ryanodine receptor 1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Ryanodine receptor 1 based upon sequence from Human
Host: QP6633 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Ryanodine receptor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6633.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - Ser534
Amino Acid Sequence: MGDAEGEDEV QFLRTDDEVV LQCSATVLKE QLKLCLAAEG FGNRLCFLEP TSNAQNVPPD LAICCFVLEQ SLSVRALQEM LANTVEAGVE SSQGGGHRTL LYGHAILLRH AHSRMYLSCL TTSRSMTDKL AFDVGLQEDA TGEACWWTMH PASKQRSEGE KVRVGDDIIL VSVSSERYLH LSTASGELQV DASFMQTLWN MNPICSRCEE GFVTGGHVLR LFHGHMDECL TISPADSDDQ RRLVYYEGGA VCTHARSLWR LEPLRISWSG SHLRWGQPLR VRHVTTGQYL ALTEDQGLVV VDASKAHTKA TSFCFRISKE KLDVAPKRDV EGMGPPEIKY GESLCFVQHV ASGLWLTYAA PDPKALRLGV LKKKAMLHQE GHMDDALSLT RCQQEESQAA RMIHSTNGLY NQFIKSLDSF SGKPRGSGPP AGTALPIEGV ILSLQDLIIY FEPPSEDLQH EEKQSKLRSL RNRQSLFQEE GMLSMVLNCI DRLNVYTTAA HFAEFAGEEA AESWKEIVNL LYELLASLIR GNRS
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Ryanodine receptor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Ryanodine receptor 1 Protein

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