SDS-PAGE separation of QP6637 followed by commassie total protein stain results in a primary band consistent with reported data for S100A12 / CAGC / Calgranulin-C Protein. These data demonstrate Greater than 80% as determined by SDS-PAGE.
SDS-PAGE separation of QP6637 followed by commassie total protein stain results in a primary band consistent with reported data for S100A12 / CAGC / Calgranulin-C Protein. These data demonstrate Greater than 80% as determined by SDS-PAGE.

Recombinant Human S100A12 / CAGC / Calgranulin-C Protein

$ 148.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6637
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: GST
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 92

Product NumberDescriptionPrice
QP6637-ec-10ug Size: 10 ug, Tag: GST $ 148.00
QP6637-ec-50ug Size: 50 ug, Tag: GST $ 218.00
QP6637-ec-100ug Size: 100 ug, Tag: GST $ 378.00
QP6637-ec-200ug Size: 200 ug, Tag: GST $ 628.00
QP6637-ec-500ug Size: 500 ug, Tag: GST $ 1,098.00
QP6637-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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SKU: QP6637-ec-10ug
Recombinant Human S100A12 / CAGC / Calgranulin-C Protein Protein General Information
Alternate Names
S100A12, CAGC, Calgranulin-C Protein, p6, CAAF1, MRP6, CAGC, CGRP, ENRAGE, MRP-6
Curated Database and Bioinformatic Data
Gene SymbolS100A12
Entrez Gene ID6283
Ensemble Gene IDENSG00000163221
RefSeq Protein Accession(s)NP_005612.1
RefSeq mRNA Accession(s)NM_005621.1
UniProt ID(s)P80511
UniGene ID(s)Hs.19413
HGNC ID(s)HGNC:10489
COSMIC ID Link(s)S100A12
KEGG Gene ID(s)hsa:6283
PharmGKB ID(s)PA34901
General Description of Recombinant Human S100A12 / CAGC / Calgranulin-C Protein Protein.
S100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. Its proinflammatory activity involves recruitment of leukocytes, promotion of cytokine and chemokine production, and regulation of leukocyte adhesion and migration. Acts as an alarmin or a danger associated molecular pattern (DAMP) molecule and stimulates innate immune cells via binding to receptor for advanced glycation endproducts (AGER). Binding to AGER activates the MAP-kinase and NF-kappa-B signaling pathways leading to production of proinflammatory cytokines and up-regulation of cell adhesion molecules ICAM1 and VCAM1. Acts as a monocyte and mast cell chemoattractant. Can stimulate mast cell degranulation and activation which generates chemokines, histamine and cytokines inducing further leukocyte recruitment to the sites of inflammation. Can inhibit the activity of matrix metalloproteinases; MMP2, MMP3 and MMP9 by chelating Zn2+ from their active sites. Possesses filariacidal and filariastatic activity. Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus

Human S100A12 / CAGC / Calgranulin-C Protein Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant S100A12 / CAGC / Calgranulin-C Protein based upon sequence from Human
Host: QP6637 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) S100A12 / CAGC / Calgranulin-C Protein, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6637.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: TKLEEHLEGI VNIFHQYSVR KGHFDTLSKG ELKQLLTKEL ANTIKNIKDK AVIDEIFQGL DANQDEQVDF QEFISLVAIA LKAAHYHTHK E
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human S100A12 / CAGC / Calgranulin-C Protein Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human S100A12 / CAGC / Calgranulin-C Protein

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