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SDS-PAGE separation of QP6757 followed by commassie total protein stain results in a primary band consistent with reported data for Synaptotagmin-1. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP6757 followed by commassie total protein stain results in a primary band consistent with reported data for Synaptotagmin-1. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Synaptotagmin-1 Protein

$ 398.00 – $ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP6757
Species: Human
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 318

Product NumberDescriptionPrice
QP6757-ec-100ug Size: 100 ug, Tag: His $ 398.00
QP6757-ec-1mg Size: 1 mg, Tag: His $ 1,728.00
Shipping Information
2-4 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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SKU: QP6757-ec-10ug
Recombinant Human Synaptotagmin-1 Protein General Information
Alternate Names
SVP65, SYT, P65
Curated Database and Bioinformatic Data
Gene SymbolSYT1
Entrez Gene ID6857
Ensemble Gene IDENSG00000067715
RefSeq Protein Accession(s)NP_001129277.1
RefSeq mRNA Accession(s)NM_001135805.1, NM_001135806.1, NM_005639.2, XM_011538710.1, XM_017019909.1
UniProt ID(s)P21579
UniGene ID(s)Hs.310545
HGNC ID(s)HGNC:11509
COSMIC ID Link(s)SYT1
KEGG Gene ID(s)hsa:6857
PharmGKB ID(s)PA36290
General Description of Recombinant Human Synaptotagmin-1 Protein.
May have a regulatory role in the mbrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2.

Human Synaptotagmin-1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Synaptotagmin-1 based upon sequence from Human
Host: QP6757 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Synaptotagmin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6757.
Bioactivity Data: Untested
Full Length? Cytoplasmic Domain
Expression Region: Lys99 - Ala416
Amino Acid Sequence: KNAINMKDVK DLGKTMKDQA LKDDDAETGL TDGEEKEEPK EEEKLGKLQY SLDYDFQNNQ LLVGIIQAAE LPALDMGGTS DPYVKVFLLP DKKKKFETKV HRKTLNPVFN EQFTFKVPYS ELGGKTLVMA VYDFDRFSKH DIIGEFKVPM NTVDFGHVTE EWRDLQSAEK EEQEKLGDIC FSLRYVPTAG KLTVVILEAK NLKKMDVGGL SDPYVKIHLM QNGKRLKKKK TTIKKNTLNP YYNESFSFEV PFEQIQKVQV VVTVLDYDKI GKNDAIGKVF VGYNSTGAEL RHWSDMLANP RRPIAQWHTL QVEEEVDA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Synaptotagmin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Synaptotagmin-1 Protein

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