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Recombinant P. aeruginosa Protease LasA Protein

$ 408.00$ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP7030
Species: P. aeruginosa
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 182

Product NumberDescriptionPrice
QP7030-20ug Size: 20 ug, Tag: His-SUMO $ 408.00
QP7030-100ug Size: 100 ug, Tag: His-SUMO $ 728.00
QP7030-1mg Size: 1 mg, Tag: His-SUMO $ 2,468.00
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Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP7030-ec-50ug
Recombinant P. aeruginosa Protease LasA Protein General Information
Alternate Names
PA1871
Curated Database and Bioinformatic Data
Gene Symbol lasA
Entrez Gene ID 878260
RefSeq Protein Accession(s) NP_250562.1
RefSeq mRNA Accession(s) NC_002516.2
UniProt ID(s) P14789
KEGG Gene ID(s) pae:PA1871
General Description of Recombinant P. aeruginosa Protease LasA Protein.
Involved in proteolysis and elastolysis (degradation of the host protein elastin). Has staphylolytic activity (degrades pentaglycine cross-links in cell wall peptidogylcan), preferring Gly-Gly-|-X substrates where X is Ala or Gly (PubMed:11179971). Enhances the elastolytic but not proteolytic activity of elastase (lasB) and elastolytic activity of other proteases (PubMed:2110137). Degradation of host elastin is likely to contribute to the pathogenicity of P.aeruginosa. While either His-317 or His-356 can abstract a proton in the hydrolysis reaction, the same residue performs both functions in a given catalytic cycle, with the other stabilizing the catalytic intermediate

P. aeruginosa Protease LasA Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Protease LasA based upon sequence from: P. aeruginosa
Host: QP7030 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) Protease LasA, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7030.
Bioactivity Data: Untested
Full Length? Full Length of Mature Protein
Expression Region: Ala237 - Leu418
Amino Acid Sequence: APPSNLMQLP WRQGYSWQPN GAHSNTGSGY PYSSFDASYD WPRWGSATYS VVAAHAGTVR VLSRCQVRVT HPSGWATNYY HMDQIQVSNG QQVSADTKLG VYAGNINTAL CEGGSSTGPH LHFSLLYNGA FVSLQGASFG PYRINVGTSN YDNDCRRYYF YNQSAGTTHC AFRPLYNPGL AL
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of P. aeruginosa Protease LasA Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant P. aeruginosa Protease LasA Protein