SDS-PAGE separation of QP7054 followed by commassie total protein stain results in a primary band consistent with reported data for Latent membrane protein 2. These data demonstrate Greater than 80% as determined by SDS-PAGE.
SDS-PAGE separation of QP7054 followed by commassie total protein stain results in a primary band consistent with reported data for Latent membrane protein 2. These data demonstrate Greater than 80% as determined by SDS-PAGE.

Recombinant Epstein-Barr Latent membrane protein 1

$ 328.00$ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP7054
Species: Epstein-Barr
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His, His-B2M
Host: E.coli, Yeast.
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 147

Product NumberDescriptionPrice
QP7054-ye-50ug Size: 10 ug, Tag: His $ 328.00
QP7054-ye-100ug Size: 50 ug, Tag: His $ 828.00
QP7054-ye-500ug Size: 200 ug, Tag: His $ 1,918.00
QP7054-ec-100ug Size: 50 ug, Tag: His-B2M $ 728.00
QP7054-ec-1mg Size: 500 ug, Tag: His-B2M $ 2,468.00
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP7054-ye-50ug
Recombinant Epstein-Barr Latent membrane protein 2 Protein General Information
Curated Database and Bioinformatic Data
Gene SymbolLMP2
Entrez Gene ID17494212
RefSeq Protein Accession(s)YP_401631.1
RefSeq mRNA Accession(s)NC_007605.1
UniProt ID(s)P13285
KEGG Gene ID(s)vg:17494212
General Description of Recombinant Epstein-Barr Latent membrane protein 2 Protein.
Isoform LMP2A maintains EBV latent infection of B-lymphocyte, by preventing lytic reactivation of the virus in response to surface immunoglobulin (sIg) cross-linking. Acts like a dominant negative inhibitor of the sIg-associated protein tyrosine kinases, LYN and SYK. Also blocks translocation of the B-cell antigen receptor (BCR) into lipid rafts, preventing the subsequent signaling and accelerated internalization of the BCR upon BCR cross-linking. Serves as a molecular scaffold to recruit SYK, LYN and E3 protein-ubiquitin ligases, such as ITCH and NEDD4L, leading to ubiquitination and potential degradation of both tyrosines kinases. Possesses a constitutive signaling activity in non-transformed cells, inducing bypass of normal B lymphocyte developmental checkpoints allowing immunoglobulin-negative cells to colonize peripheral lymphoid organs. Isoform LMP2B may be a negative regulator of isoform LMP2A.

Epstein-Barr Latent membrane protein 2 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Latent membrane protein 2 based upon sequence from: Epstein-Barr
Host: QP7054 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4) Latent membrane protein 2, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7054.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - Ser147
Amino Acid Sequence: MGSLEMVPMG AGPPSPGGDP DGYDGGNNSQ YPSASGSSGN TPTPPNDEER ESNEEPPPPY EDPYWGNGDR HSDYQPLGTQ DQSLYLGLQH DGNDGLPPPP YSPRDDSSQH IYEEAGRGSM NPVCLPVIVA PYLFWLAAIA ASCFTAS
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Epstein-Barr Latent membrane protein 2 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Epstein-Barr Latent membrane protein 1

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