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Recombinant Influenza A H1N1 (Fort Warren / 1 / 1950) Nucleocapsid Protein

$ 288.00$ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP7081
Species: Influenza
Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 498

Product NumberDescriptionPrice
QP7081-10ug Size: 10 ug, Tag: His-SUMO $ 288.00
QP7081-50ug Size: 50 ug, Tag: His-SUMO $ 408.00
QP7081-100ug Size: 100 ug, Tag: His-SUMO $ 708.00
QP7081-200ug Size: 200 ug, Tag: His-SUMO $ 1,158.00
QP7081-500ug Size: 500 ug, Tag: His-SUMO $ 1,548.00
QP7081-1mg Size: 1 mg, Tag: His-SUMO $ 2,468.00
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Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP7081-ec-50ug
Recombinant Influenza Influenza A H1N1 (strain A / Fort Warren / 1 / 1950) Nucleocapsid Protein General Information
Curated Database and Bioinformatic Data
Gene SymbolNP
UniProt ID(s)P18071
General Description of Recombinant Influenza Influenza A H1N1 (strain A / Fort Warren / 1 / 1950) Nucleocapsid Protein.
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus (By similarity).

Influenza Influenza A H1N1 (strain A / Fort Warren / 1 / 1950) Nucleocapsid Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Influenza A H1N1 (strain A / Fort Warren / 1 / 1950) Nucleocapsid based upon sequence from: Influenza
Host: QP7081 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Influenza A virus (strain A/Fort Warren/1/1950 H1N1) Influenza A H1N1 (strain A/Fort Warren/1/1950) Nucleocapsid, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP7081.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Asn498
Amino Acid Sequence: MASQGTKRSY EQMETDGDRQ NATEIRASVG KMIDGIGRFY IQMCTELKLS DYEGRLIQNS LTIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPIYKRV DGKWMRELVL YDKEEIRRIW RQANNGDDAT AGLTHMMIWH SNLNDTTYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTMV MELIRMIKRG INDRNFWRGE NGRKTRIAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN AEIEDLIFLA RSALILRGSV AHKSCLPACV YGPAVASGYD FEKEGYSLVG IDPFKLLQNS QVYSLIRPNE NPAHKSQLVW MACNSAAFED LRVSSFIRGT KVIPRGKLST RGVQIASNEN MDTMGSSTLE LRSRYWAIRT RSGGNTNQQR ASAGQISIQP TFSVQRNLPF DKTTIMAAFT GNAEGRTSDM RAEIIRMMES ARPEEVSFQG RGVFELSDER AANPIVPSFD MSNEGSYFFG DNAEEYDN
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Influenza Influenza A H1N1 (strain A / Fort Warren / 1 / 1950) Nucleocapsid Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Influenza A H1N1 (Fort Warren / 1 / 1950) Nucleocapsid Protein