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SDS-PAGE separation of QP7221 followed by commassie total protein stain results in a primary band consistent with reported data for Thyroxine 5-deiodinase. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP7221 followed by commassie total protein stain results in a primary band consistent with reported data for Thyroxine 5-deiodinase. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Rat Thyroxine 5-deiodinase Protein

$ 578.00 – $ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP7221
Species: Rat
Available Tags: His
Host: E.coli, Yeast.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 242

Product NumberDescriptionPrice
QP7221-ec-100ug Size: 100 ug, Tag: His $ 578.00
QP7221-ec-1mg Size: 1 mg, Tag: His $ 2,468.00
QP7221-ye-100ug Size: 100 ug, Tag: His $ 578.00
QP7221-ye-500ug Size: 500 ug, Tag: His $ 1,588.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP7221-ec-10ug
Recombinant Rat Thyroxine 5-deiodinase Protein General Information
Alternate Names
5DIII; DIOIII
Curated Database and Bioinformatic Data
Gene SymbolDio3
Entrez Gene ID29475
RefSeq Protein Accession(s)NP_058906.3
RefSeq mRNA Accession(s)NM_017210.4
UniProt ID(s)P49897
UniGene ID(s)Rn.11237
COSMIC ID Link(s)Dio3
KEGG Gene ID(s)rno:29475
General Description of Recombinant Rat Thyroxine 5-deiodinase Protein.
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing prature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during bryological development.

Rat Thyroxine 5-deiodinase Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Thyroxine 5-deiodinase based upon sequence from: Rat
Host: QP7221 protein expressed in E.coli, Yeast..
Tag: His
Protein Construction: A DNA sequence encoding the Rattus norvegicus (Rat) Thyroxine 5-deiodinase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7221.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Asp37 - Leu278
Amino Acid Sequence: DFLCIRKHFL RRRHPDHPEP EVELNSEGEE MPPDDPPICV SDDNRLCTLA SLKAVWHGQK LDFFKQAHEG GPAPNSEVVR PDGFQSQRIL DYAQGTRPLV LNFGSCTUPP FMARMSAFQR LVTKYQRDVD FLIIYIEEAH PSDGWVTTDS PYVIPQHRSL EDRVSAARVL QQGAPGCALV LDTMANSSSS AYGAYFERLY VIQSGTIMYQ GGRGPDGYQV SELRTWLERY DEQLHGTRPR RL
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Rat Thyroxine 5-deiodinase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Rat Thyroxine 5-deiodinase Protein

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