SDS-PAGE separation of QP7399 followed by commassie total protein stain results in a primary band consistent with reported data for Complement C3. These data demonstrate Greater than 80% as determined by SDS-PAGE.
SDS-PAGE separation of QP7399 followed by commassie total protein stain results in a primary band consistent with reported data for Complement C3. These data demonstrate Greater than 80% as determined by SDS-PAGE.

Recombinant Mouse Complement C3 Protein

$ 238.00$ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP7399
Species: Mouse
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 343

Product NumberDescriptionPrice
QP7399-ec-10ug Size: 10 ug, Tag: His-SUMO $ 238.00
QP7399-ec-100ug Size: 100 ug, Tag: His-SUMO $ 578.00
QP7399-ec-1mg Size: 1 mg, Tag: His-SUMO $ 2,468.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP7399-ec-10ug
Recombinant Mouse Complement C3 Protein General Information
Alternate Names
ASP; HSE-MSF; Plp; AI255234
Curated Database and Bioinformatic Data
Gene SymbolC3
Entrez Gene ID12266
Ensemble Gene IDENSMUSG00000024164
RefSeq Protein Accession(s)NP_033908.2
RefSeq mRNA Accession(s)NM_009778.3
UniProt ID(s)P01027
UniGene ID(s)Mm.19131
COSMIC ID Link(s)C3
KEGG Gene ID(s)mmu:12266
General Description of Recombinant Mouse Complement C3 Protein.
C3 plays a central role in the activation of the complent syst. Its processing by C3 convertase is the central reaction in both classical and alternative complent pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.Derived from proteolytic degradation of complent C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a choattractant for neutrophils . It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. The short isoform has B-cell stimulatory activity.C3-beta-c: Acts as a choattractant for neutrophils in chronic inflammation.Acylation stimulating protein: adipogenic hormone that stimulates triglyceride (TG) synthesis and glucose transport in adipocytes, regulating fat storage and playing a role in postprandial TG clearance. Appears to stimulate TG synthesis via activation of the PLC, MAPK and AKT signaling pathways. Ligand for C5AR2. Promotes the phosphorylation, ARRB2-mediated internalization and recycling of C5AR2.

Mouse Complement C3 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Complement C3 based upon sequence from: Mouse
Host: QP7399 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Mus musculus (Mouse) Complement C3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7399.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser1321 - Asn1663
Amino Acid Sequence: SEETKQNEAF SLTAKGKGRG TLSVVAVYHA KLKSKVTCKK FDLRVSIRPA PETAKKPEEA KNTMFLEICT KYLGDVDATM SILDISMMTG FAPDTKDLEL LASGVDRYIS KYEMNKAFSN KNTLIIYLEK ISHTEEDCLT FKVHQYFNVG LIQPGSVKVY SYYNLEESCT RFYHPEKDDG MLSKLCHSEM CRCAEENCFM QQSQEKINLN VRLDKACEPG VDYVYKTELT NIELLDDFDE YTMTIQQVIK SGSDEVQAGQ QRKFISHIKC RNALKLQKGK KYLMWGLSSD LWGEKPNTSY IIGKDTWVEH WPEAEECQDQ KYQKQCEELG AFTESMVVYG CPN
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Mouse Complement C3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Mouse Complement C3 Protein

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