Additional SEQUEST analysis of the LC MS/MS spectra from QP7410 identified an additional between this protein and the spectra of another peptide sequence that matches a region of Protein E7 confirming successful recombinant synthesis.

SDS-PAGE separation of QP7410 followed by commassie total protein stain results in a primary band consistent with reported data for Protein E7. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Protein E7

$ 158.00 – $ 1,728.00

Please Select Product Options Below To View The Catalog Number.

SKU: QP7410
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 98

Product Number	Description	Price
QP7410-ec-10ug	Size: 10 ug, Tag: His	$ 158.00
QP7410-ec-100ug	Size: 100 ug, Tag: His	$ 398.00
QP7410-ec-1mg	Size: 1 mg, Tag: His	$ 1,728.00

Shipping Information

On Demand Protein: 3-5 Week Lead Time. (Why?)

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: QP7410-ec-10ug

Recombinant Human Protein E7 Protein (1-98aa) General Information
Alternate Names
HpV16gp2
Curated Database and Bioinformatic Data
Gene Symbol	E7
Entrez Gene ID	1489079
RefSeq Protein Accession(s)	NP_041326.1
RefSeq mRNA Accession(s)	NC_001526.4
UniProt ID(s)	P03129
KEGG Gene ID(s)	vg:1489079
General Description of Recombinant Human Protein E7 Protein (1-98aa).
E7 protein has both transforming and trans-activating activities. Disrupts the function of host retinoblastoma protein RB1/pRb, which is a key regulator of the cell cycle. Induces the disassbly of the E2F1 transcription factors from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. Interferes with histone deacetylation mediated by HDAC1 and HDAC2, leading to activation of transcription .

Human Protein E7 Recombinant Protein Product Attributes

Product Type: Recombinant Protein

Recombinant Protein E7 based upon sequence from: Human

Host: QP7410 protein expressed in E. coli.

Tag: His

Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Protein E7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.

Application Notes: Please contact us for application specific information for QP7410.

Bioactivity Data: Untested

Full Length? Full Length

Expression Region: Met1 - Pro98

Amino Acid Sequence: MHGDTPTLHE YMLDLQPETT DLYCYEQLND SSEEEDEIDG PAGQAEPDRA HYNIVTFCCK CDSTLRLCVQ STHVDIRTLE DLLMGTLGIV CPICSQKP

Purity: Greater than 90% as determined by SDS-PAGE.

Reconstitution Instructions:

Concentration of Human Protein E7 Protein:

Endotoxin Levels: Not determined.

Buffer: Tris-based buffer, 50% glycerol

Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

There are no reviews yet.