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SDS-PAGE separation of QP7553 followed by commassie total protein stain results in a primary band consistent with reported data for Transcriptional enhancer factor TEF-3. These data demonstrate Greater than 80% as determined by SDS-PAGE.
SDS-PAGE separation of QP7553 followed by commassie total protein stain results in a primary band consistent with reported data for Transcriptional enhancer factor TEF-3. These data demonstrate Greater than 80% as determined by SDS-PAGE.

Recombinant Human Transcriptional enhancer factor TEF-3 Protein

$ 398.00 – $ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP7553
Species: Human
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 361

Product NumberDescriptionPrice
QP7553-ec-100ug Size: 100 ug, Tag: His-SUMO $ 448.00
QP7553-ec-1mg Size: 1 mg, Tag: His-SUMO $ 1,938.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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SKU: QP7553-ec-10ug
Recombinant Human Transcriptional enhancer factor TEF-3 Protein General Information
Alternate Names
TEF-3; EFTR-2; TEF3; RTEF1; TEFR-1; hRTEF-1B; TCF13L1
Curated Database and Bioinformatic Data
Gene SymbolTEAD4
Entrez Gene ID7004
Ensemble Gene IDENSG00000197905
RefSeq Protein Accession(s)NP_003204.2
RefSeq mRNA Accession(s)NM_003213.3, NM_201441.2, NM_201443.2
UniProt ID(s)Q15561
UniGene ID(s)Hs.94865
HGNC ID(s)HGNC:11717
COSMIC ID Link(s)TEAD4
KEGG Gene ID(s)hsa:7004
PharmGKB ID(s)PA36435
General Description of Recombinant Human Transcriptional enhancer factor TEF-3 Protein.
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (T) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.

Human Transcriptional enhancer factor TEF-3 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Transcriptional enhancer factor TEF-3 based upon sequence from: Human
Host: QP7553 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Transcriptional enhancer factor TEF-3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7553.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met74 - Glu434
Amino Acid Sequence: MYGRNELIAR YIKLRTGKTR TRKQVSSHIQ VLARRKAREI QAKLKDQAAK DKALQSMAAM SSAQIISATA FHSSMALARG PGRPAVSGFW QGALPGQAGT SHDVKPFSQQ TYAVQPPLPL PGFESPAGPA PSPSAPPAPP WQGRSVASSK LWMLEFSAFL EQQQDPDTYN KHLFVHIGQS SPSYSDPYLE AVDIRQIYDK FPEKKGGLKD LFERGPSNAF FLVKFWADLN TNIEDEGSSF YGVSSQYESP ENMIITCSTK VCSFGKQVVE KVETEYARYE NGHYSYRIHR SPLCEYMINF IHKLKHLPEK YMMNSVLENF TILQVVTNRD TQETLLCIAY VFEVSASEHG AQHHIYRLVK E
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Transcriptional enhancer factor TEF-3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Transcriptional enhancer factor TEF-3 Protein

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