SEQUEST analysis of LC MS/MS spectra obtained from a run with QP7657 identified a match between this protein and the spectra of a peptide sequence that matches a region of TIGIT / VSTM3.
SEQUEST analysis of LC MS/MS spectra obtained from a run with QP7657 identified a match between this protein and the spectra of a peptide sequence that matches a region of TIGIT / VSTM3.Additional SEQUEST analysis of the LC MS/MS spectra from QP7657 identified an additional between this protein and the spectra of another peptide sequence that matches a region of TIGIT / VSTM3 confirming successful recombinant synthesis.SDS-PAGE separation of QP7657 followed by commassie total protein stain results in a primary band consistent with reported data for TIGIT / VSTM3. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human TIGIT / VSTM3 Protein

$ 578.00$ 2,468.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP7657
Species: Human
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 120

Product NumberDescriptionPrice
QP7657-ec-100ug Size: 100 ug, Tag: His-SUMO $ 578.00
QP7657-ec-1mg Size: 1 mg, Tag: His-SUMO $ 2,468.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP7657-ec-10ug
Recombinant Human TIGIT / VSTM3 Protein General Information
Alternate Names
TIGIT; VSTM3; Vstm3; ENSMUSG00000071552
Curated Database and Bioinformatic Data
Gene SymbolTIGIT
Entrez Gene ID201633
Ensemble Gene IDENSG00000181847
RefSeq Protein Accession(s)NP_776160.2
RefSeq mRNA Accession(s)NM_173799.3
UniProt ID(s)Q495A1
UniGene ID(s)Hs.421750
HGNC ID(s)HGNC:26838
COSMIC ID Link(s)TIGIT
KEGG Gene ID(s)hsa:201633
PharmGKB ID(s)PA164726482
General Description of Recombinant Human TIGIT / VSTM3 Protein.
Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Human TIGIT / VSTM3 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant TIGIT / VSTM3 based upon sequence from: Human
Host: QP7657 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) TIGIT / VSTM3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7657.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Met22 - Pro141
Amino Acid Sequence: MMTGTIETTG NISAEKGGSI ILQCHLSSTT AQVTQVNWEQ QDQLLAICNA DLGWHISPSF KDRVAPGPGL GLTLQSLTVN DTGEYFCIYH TYPDGTYTGR IFLEVLESSV AEHGARFQIP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human TIGIT / VSTM3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human TIGIT / VSTM3 Protein

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