SDS-PAGE separation of QP7837 followed by commassie total protein stain results in a primary band consistent with reported data for Dystonin. These data demonstrate Greater than 90% as determined by SDS-PAGE.
SDS-PAGE separation of QP7837 followed by commassie total protein stain results in a primary band consistent with reported data for Dystonin. These data demonstrate Greater than 90% as determined by SDS-PAGE.

Recombinant Human Dystonin Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP7837
Species: Human
Available Tags: His-SUMO, His
Host: E.coli, Yeast.
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 195

Product NumberDescriptionPrice
QP7837-ec-100ug Size: 100 ug, Tag: His-SUMO $ 398.00
QP7837-ec-1mg Size: 1 mg, Tag: His-SUMO $ 1,728.00
QP7837-ye-100ug Size: 100 ug, Tag: His $ 468.00
QP7837-ye-500ug Size: 500 ug, Tag: His $ 1,298.00
Shipping Information
7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP7837-ec-10ug
Recombinant Human Dystonin Protein General Information
Alternate Names
CATX-15; MACF2; BPAG1; BP240; BPA; HSAN6; CATX15; D6S1101; DMH; DT; EBSB2
Curated Database and Bioinformatic Data
Gene SymbolDST
Entrez Gene ID667
Ensemble Gene IDENSG00000151914
RefSeq Protein Accession(s)NP_001138241.1
RefSeq mRNA Accession(s)NM_001144769.2, NM_001144770.1, NM_001723.5, NM_015548.4, NM_183380.3, XM_017011224.1
UniProt ID(s)Q03001
UniGene ID(s)Hs.604915
HGNC ID(s)HGNC:1090
COSMIC ID Link(s)DST
KEGG Gene ID(s)hsa:667
PharmGKB ID(s)PA25399
General Description of Recombinant Human Dystonin Protein.
Cytoskeletal linker protein. Acts as an integrator of intermediate filaments, actin and microtubule cytoskeleton networks. Required for anchoring either intermediate filaments to the actin cytoskeleton in neural and muscle cells or keratin-containing intermediate filaments to hemidesmosomes in epithelial cells. The proteins may self-aggregate to form filaments or a two-dimensional mesh. Isoform 3: plays a structural role in the assembly of hemidesmosomes of epithelial cells; anchors keratin-containing intermediate filaments to the inner plaque of hemidesmosomes. Required for the regulation of keratinocyte polarity and motility; mediates integrin ITGB4 regulation of RAC1 activity. Isoform 6: required for bundling actin filaments around the nucleus.By similarity3 Publications Isoform 7: regulates the organization and stability of the microtubule network of sensory neurons to allow axonal transport.

Human Dystonin Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Dystonin based upon sequence from: Human
Host: QP7837 protein expressed in E.coli, Yeast..
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Dystonin, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7837.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 - Pro195
Amino Acid Sequence: MAGYLSPAAY LYVEEQEYLQ AYEDVLERYK DERDKVQKKT FTKWINQHLM KVRKHVNDLY EDLRDGHNLI SLLEVLSGDT LPREKGRMRF HRLQNVQIAL DYLKRRQVKL VNIRNDDITD GNPKLTLGLI WTIILHFQIS DIHVTGESED MSAKERLLLW TQQATEGYAG IRCENFTTCW RDGKLFNAII HKYRP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Dystonin Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Dystonin Protein

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