SDS-PAGE separation of QP8032 followed by commassie total protein stain results in a primary band consistent with reported data for Transcriptional enhancer factor TEF-5. These data demonstrate Greater than 80% as determined by SDS-PAGE.
SDS-PAGE separation of QP8032 followed by commassie total protein stain results in a primary band consistent with reported data for Transcriptional enhancer factor TEF-5. These data demonstrate Greater than 80% as determined by SDS-PAGE.

Recombinant Human Transcriptional enhancer factor TEF-5 Protein

$ 398.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8032
Species: Human
Available Tags: His-SUMO
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 324

Product NumberDescriptionPrice
QP8032-ec-100ug Size: 100 ug, Tag: His-SUMO $ 398.00
QP8032-ec-1mg Size: 1 mg, Tag: His-SUMO $ 1,728.00
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7-10 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
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SKU: QP8032-ec-10ug
Recombinant Human Transcriptional enhancer factor TEF-5 Protein General Information
Alternate Names
TEAD5; TEAD-3; TEF-5; ETFR-1; DTEF-1; TEF5
Curated Database and Bioinformatic Data
Gene SymbolTEAD3
Entrez Gene ID7005
Ensemble Gene IDENSG00000007866
RefSeq Protein Accession(s)NP_003205.2
RefSeq mRNA Accession(s)NM_003214.3
UniProt ID(s)Q99594
UniGene ID(s)Hs.485205
HGNC ID(s)HGNC:11716
COSMIC ID Link(s)TEAD3
KEGG Gene ID(s)hsa:7005
PharmGKB ID(s)PA36434
General Description of Recombinant Human Transcriptional enhancer factor TEF-5 Protein.
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (T) induction. Binds to multiple functional elents of the human chorionic somatomammotropin-B gene enhancer.

Human Transcriptional enhancer factor TEF-5 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Transcriptional enhancer factor TEF-5 based upon sequence from: Human
Host: QP8032 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Transcriptional enhancer factor TEF-5, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8032.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met112 - Asp435
Amino Acid Sequence: MNLDQVSKDK ALQSMASMSS AQIVSASVLQ NKFSPPSPLP QAVFSTSSRF WSSPPLLGQQ PGPSQDIKPF AQPAYPIQPP LPPTLSSYEP LAPLPSAAAS VPVWQDRTIA SSRLRLLEYS AFMEVQRDPD TYSKHLFVHI GQTNPAFSDP PLEAVDVRQI YDKFPEKKGG LKELYEKGPP NAFFLVKFWA DLNSTIQEGP GAFYGVSSQY SSADSMTISV STKVCSFGKQ VVEKVETEYA RLENGRFVYR IHRSPMCEYM INFIHKLKHL PEKYMMNSVL ENFTILQVVT SRDSQETLLV IAFVFEVSTS EHGAQHHVYK LVKD
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Transcriptional enhancer factor TEF-5 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Transcriptional enhancer factor TEF-5 Protein

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