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Recombinant Human Spindlin-1 Protein

$ 448.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8292
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 80% as determined by SDS-PAGE.
Length (Amino Acids): 262

Product NumberDescriptionPrice
QP8292-ec-100ug Size: 100 ug, Tag: GST $ 448.00
QP8292-ec-1mg Size: 1 mg, Tag: GST $ 1,938.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8292-ec-10ug
Recombinant Human Spindlin-1 Protein General Information
Alternate Names
TDRD24; SPIN
Curated Database and Bioinformatic Data
Gene SymbolSPIN1
Entrez Gene ID10927
Ensemble Gene IDENSG00000106723
RefSeq Protein Accession(s)NP_006708.2
RefSeq mRNA Accession(s)NM_006717.2
UniProt ID(s)Q9Y657
UniGene ID(s)Hs.146804
HGNC ID(s)HGNC:11243
COSMIC ID Link(s)SPIN1
KEGG Gene ID(s)hsa:10927
PharmGKB ID(s)PA162404504
General Description of Recombinant Human Spindlin-1 Protein.
Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway downstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway. Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes. May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.

Human Spindlin-1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Spindlin-1 based upon sequence from: Human
Host: QP8292 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Spindlin-1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8292.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 - Ser262
Amino Acid Sequence: MKTPFGKTPG QRSRADAGHA GVSANMMKKR TSHKKHRSSV GPSKPVSQPR RNIVGCRIQH GWKEGNGPVT QWKGTVLDQV PVNPSLYLIK YDGFDCVYGL ELNKDERVSA LEVLPDRVAT SRISDAHLAD TMIGKAVEHM FETEDGSKDE WRGMVLARAP VMNTWFYITY EKDPVLYMYQ LLDDYKEGDL RIMPDSNDSP PAEREPGEVV DSLVGKQVEY AKEDGSKRTG MVIHQVEAKP SVYFIKFDDD FHIYVYDLVK TS
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Spindlin-1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Spindlin-1 Protein