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Recombinant Human GAPDH Protein

$ 448.00 – $ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8304
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 333

Product NumberDescriptionPrice
QP8304-ec-100ug Size: 100 ug, Tag: GST $ 398.00
QP8304-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8304-ec-10ug
Recombinant Human GAPDH Protein (3-335aa) General Information
Alternate Names
GAPDH; G3PD; HEL-S-162eP; GAPD
Curated Database and Bioinformatic Data
Gene SymbolGAPDH
Entrez Gene ID2597
Ensemble Gene IDENSG00000111640
RefSeq Protein Accession(s)NP_001243728.1
RefSeq mRNA Accession(s)NM_001256799.2, NM_001289745.1, NM_001289746.1, NM_002046.5
UniProt ID(s)P04406
UniGene ID(s)Hs.544577
HGNC ID(s)HGNC:4141
COSMIC ID Link(s)GAPDH
KEGG Gene ID(s)hsa:2597
PharmGKB ID(s)PA28554
General Description of Recombinant Human GAPDH Protein (3-335aa).
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assbly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and mbrane associations through its ability to stimulate the binding of CHP1 to microtubules . Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assbles into the GAIT complex which binds to st loop-containing GAIT elents in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.3 Publications

Human GAPDH Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant GAPDH based upon sequence from: Human
Host: QP8304 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GAPDH, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8304.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Lys3 - Glu335
Amino Acid Sequence: KVKVGVNGFG RIGRLVTRAA FNSGKVDIVA INDPFIDLNY MVYMFQYDST HGKFHGTVKA ENGKLVINGN PITIFQERDP SKIKWGDAGA EYVVESTGVF TTMEKAGAHL QGGAKRVIIS APSADAPMFV MGVNHEKYDN SLKIISNASC TTNCLAPLAK VIHDNFGIVE GLMTTVHAIT ATQKTVDGPS GKLWRDGRGA LQNIIPASTG AAKAVGKVIP ELNGKLTGMA FRVPTANVSV VDLTCRLEKP AKYDDIKKVV KQASEGPLKG ILGYTEHQVV SSDFNSDTHS STFDAGAGIA LNDHFVKLIS WYDNEFGYSN RVVDLMAHMA SKE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GAPDH Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human GAPDH Protein