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Recombinant Human P4HB / ERBA2L Protein

$ 398.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8314
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 285

Product NumberDescriptionPrice
QP8314-ec-100ug Size: 100 ug, Tag: GST $ 398.00
QP8314-ec-1mg Size: 1 mg, Tag: GST $ 1,728.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8314-ec-10ug
Recombinant Human P4HB / ERBA2L Protein General Information
Alternate Names
P4HB; ERBA2L; PHDB; P4Hbeta; PO4DB; PROHB; ERBA2L; GIT; DSI; PDI; CLCRP1; PDIA1; PO4HB
Curated Database and Bioinformatic Data
Gene SymbolP4hb
Entrez Gene ID5034
Ensemble Gene IDENSG00000185624
RefSeq Protein Accession(s)NP_000909.2
RefSeq mRNA Accession(s)NM_000918.3
UniProt ID(s)P07237
UniGene ID(s)Hs.464336
HGNC ID(s)HGNC:8548
COSMIC ID Link(s)P4hb
KEGG Gene ID(s)hsa:5034
PharmGKB ID(s)PA32876
General Description of Recombinant Human P4HB / ERBA2L Protein.
This multifunctional protein catalyzes the formation, breakage and rearrangent of disulfide bonds. At the cell surface, ses to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, ses to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with other chaperones in the structural modification of the TG precursor in hormone biogenesis. Also acts a structural subunit of various enzymes such as prolyl 4-hydroxylase and microsomal triacylglycerol transfer protein MTTP.

Human P4HB / ERBA2L Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant P4HB / ERBA2L based upon sequence from: Human
Host: QP8314 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) P4HB / ERBA2L, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8314.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Leu29 - Pro313
Amino Acid Sequence: LRKSNFAEAL AAHKYLLVEF YAPWCGHCKA LAPEYAKAAG KLKAEGSEIR LAKVDATEES DLAQQYGVRG YPTIKFFRNG DTASPKEYTA GREADDIVNW LKKRTGPAAT TLPDGAAAES LVESSEVAVI GFFKDVESDS AKQFLQAAEA IDDIPFGITS NSDVFSKYQL DKDGVVLFKK FDEGRNNFEG EVTKENLLDF IKHNQLPLVI EFTEQTAPKI FGGEIKTHIL LFLPKSVSDY DGKLSNFKTA AESFKGKILF IFIDSDHTDN QRILEFFGLK KEECP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human P4HB / ERBA2L Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human P4HB / ERBA2L Protein