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Recombinant Human Thiopurine S-methyltransferase Protein

$ 148.00$ 1,728.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8325
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 241

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Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8325-ec-10ug
Recombinant Human Thiopurine S-methyltransferase Protein General Information
Alternate Names
TPMTD
Curated Database and Bioinformatic Data
Gene SymbolTPMT
Entrez Gene ID7172
Ensemble Gene IDENSG00000137364
RefSeq Protein Accession(s)NP_000358.1
RefSeq mRNA Accession(s)NM_000367.4, NM_001346817.1, NM_001346818.1
UniProt ID(s)P51580
UniGene ID(s)Hs.444319
HGNC ID(s)HGNC:12014
COSMIC ID Link(s)TPMT
KEGG Gene ID(s)hsa:7172
PharmGKB ID(s)PA356
General Description of Recombinant Human Thiopurine S-methyltransferase Protein.
Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine.

Human Thiopurine S-methyltransferase Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Thiopurine S-methyltransferase based upon sequence from: Human
Host: QP8325 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Thiopurine S-methyltransferase, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8325.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Thr4 - Glu244
Amino Acid Sequence: TRTSLDIEEY SDTEVQKNQV LTLEEWQDKW VNGKTAFHQE QGHQLLKKHL DTFLKGKSGL RVFFPLCGKA VEMKWFADRG HSVVGVEISE LGIQEFFTEQ NLSYSEEPIT EIPGTKVFKS SSGNISLYCC SIFDLPRTNI GKFDMIWDRG ALVAINPGDR KCYADTMFSL LGKKFQYLLC VLSYDPTKHP GPPFYVPHAE IERLFGKICN IRCLEKVDAF EERHKSWGID CLFEKLYLLT E
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Thiopurine S-methyltransferase Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Thiopurine S-methyltransferase Protein