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Recombinant Human GRK2 / ADRBK1 Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8340
Species: Human
Available Tags: His
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 220

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8340-ec-10ug
Recombinant Human GRK2 / ADRBK1 Protein General Information
Alternate Names
GRK2; ADRBK1; BETA-ARK1; ADRBK1; BARK1
Curated Database and Bioinformatic Data
Gene SymbolADRBK1
Entrez Gene ID156
Ensemble Gene IDENSG00000173020
RefSeq Protein Accession(s)NP_001610.2
RefSeq mRNA Accession(s)NM_001619.3
UniProt ID(s)P25098
UniGene ID(s)Hs.83636
HGNC ID(s)HGNC:289
COSMIC ID Link(s)ADRBK1
KEGG Gene ID(s)hsa:156
PharmGKB ID(s)PA40
General Description of Recombinant Human GRK2 / ADRBK1 Protein.
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of th. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.

Human GRK2 / ADRBK1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant GRK2 / ADRBK1 based upon sequence from: Human
Host: QP8340 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) GRK2 / ADRBK1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8340.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ala2 - Cys221
Amino Acid Sequence: ADLEAVLADV SYLMAMEKSK ATPAARASKK ILLPEPSIRS VMQKYLEDRG EVTFEKIFSQ KLGYLLFRDF CLNHLEEARP LVEFYEEIKK YEKLETEEER VARSREIFDS YIMKELLACS HPFSKSATEH VQGHLGKKQV PPDLFQPYIE EICQNLRGDV FQKFIESDKF TRFCQWKNVE LNIHLTMNDF SVHRIIGRGG FGEVYGCRKA DTGKMYAMKC
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human GRK2 / ADRBK1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human GRK2 / ADRBK1 Protein