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Recombinant Human U1 small nuclear ribonucleoprotein 1

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8341
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 271

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8341-ec-10ug
Recombinant Human U1 small nuclear ribonucleoprotein A Protein General Information
Alternate Names
Mud1; U1A; U1-A
Curated Database and Bioinformatic Data
Gene SymbolSNRPA
Entrez Gene ID6626
Ensemble Gene IDENSG00000077312
RefSeq Protein Accession(s)NP_004587.1
RefSeq mRNA Accession(s)NM_004596.4
UniProt ID(s)P09012
UniGene ID(s)Hs.466775
HGNC ID(s)HGNC:11151
COSMIC ID Link(s)SNRPA
KEGG Gene ID(s)hsa:6626
PharmGKB ID(s)PA35993
General Description of Recombinant Human U1 small nuclear ribonucleoprotein A Protein.
Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assbly of the spliceosome. U1 snRNP is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. SNRPA binds st loop II of U1 snRNA. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. May bind preferentially to the 5'-UGCAC-3' motif on RNAs.

Human U1 small nuclear ribonucleoprotein A Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant U1 small nuclear ribonucleoprotein A based upon sequence from: Human
Host: QP8341 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) U1 small nuclear ribonucleoprotein A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8341.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Pro8 - Ser278
Amino Acid Sequence: PNHTIYINNL NEKIKKDELK KSLYAIFSQF GQILDILVSR SLKMRGQAFV IFKEVSSATN ALRSMQGFPF YDKPMRIQYA KTDSDIIAKM KGTFVERDRK REKRKPKSQE TPATKKAVQG GGATPVVGAV QGPVPGMPPM TQAPRIMHHM PGQPPYMPPP GMIPPPGLAP GQIPPGAMPP QQLMPGQMPP AQPLSENPPN HILFLTNLPE ETNELMLSML FNQFPGFKEV RLVPGRHDIA FVEFDNEVQA GAARDALQGF KITQNNAMKI S
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human U1 small nuclear ribonucleoprotein A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human U1 small nuclear ribonucleoprotein 1