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Recombinant Human Interferon-induced transmembrane protein 1

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8354
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 36

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8354-ec-10ug
Recombinant Human Interferon-induced transmembrane protein 1 Protein General Information
Alternate Names
9-27; DSPA2a; IFI17; CD225; LEU13
Curated Database and Bioinformatic Data
Gene SymbolIFITM1
Entrez Gene ID8519
Ensemble Gene IDENSG00000185885
RefSeq Protein Accession(s)NP_003632.3
RefSeq mRNA Accession(s)NM_003641.3
UniProt ID(s)P13164
UniGene ID(s)Hs.458414
HGNC ID(s)HGNC:5412
COSMIC ID Link(s)IFITM1
KEGG Gene ID(s)hsa:8519
PharmGKB ID(s)PA29653
General Description of Recombinant Human Interferon-induced transmembrane protein 1 Protein.
IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). Can inhibit: influenza virus hagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry and SARS-CoV S protein-mediated viral entry. Also implicated in cell adhesion and control of cell growth and migration. Plays a key role in the antiproliferative action of IFN-gamma either by inhibiting the ERK activation or by arresting cell growth in G1 phase in a p53-dependent manner. Acts as a positive regulator of osteoblast differentiation

Human Interferon-induced transmembrane protein 1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Interferon-induced transmembrane protein 1 based upon sequence from: Human
Host: QP8354 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Interferon-induced transmembrane protein 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8354.
Bioactivity Data: Untested
Full Length? Extracellular Domain
Expression Region: Met1 - His36
Amino Acid Sequence: MHKEEHEVAV LGPPPSTILP RSTVINIHSE TSVPDH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Interferon-induced transmembrane protein 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Interferon-induced transmembrane protein 1