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Recombinant Human Casein kinase I isoform epsilon Protein

$ 148.00$ 1,678.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8358
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 215

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8358-ec-10ug
Recombinant Human Casein kinase I isoform epsilon Protein General Information
Alternate Names
CKIepsilon; HCKIE
Curated Database and Bioinformatic Data
Gene SymbolCSNK1E
Entrez Gene ID102800317
Ensemble Gene IDENSG00000213923
RefSeq Protein Accession(s)NP_001276841.1
RefSeq mRNA Accession(s)NM_001289912.1, NM_001894.4, NM_152221.2
UniProt ID(s)P49674
UniGene ID(s)Hs.474833
HGNC ID(s)HGNC:2453
COSMIC ID Link(s)CSNK1E
KEGG Gene ID(s)hsa:102800317
PharmGKB ID(s)PA26953
General Description of Recombinant Human Casein kinase I isoform epsilon Protein.
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.

Human Casein kinase I isoform epsilon Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Casein kinase I isoform epsilon based upon sequence from: Human
Host: QP8358 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Casein kinase I isoform epsilon, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8358.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Ser17 - Lys231
Amino Acid Sequence: SGSFGDIYLG ANIASGEEVA IKLECVKTKH PQLHIESKFY KMMQGGVGIP SIKWCGAEGD YNVMVMELLG PSLEDLFNFC SRKFSLKTVL LLADQMISRI EYIHSKNFIH RDVKPDNFLM GLGKKGNLVY IIDFGLAKKY RDARTHQHIP YRENKNLTGT ARYASINTHL GIEQSRRDDL ESLGYVLMYF NLGSLPWQGL KAATKRQKYE RISEK
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Casein kinase I isoform epsilon Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Casein kinase I isoform epsilon Protein