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Recombinant Human Rho guanine nucleotide exchange factor 7 Protein

$ 168.00$ 1,938.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8370
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 250

Product NumberDescriptionPrice
QP8370-ec-10ug Size: 10 ug, Tag: GST $ 168.00
QP8370-ec-50ug Size: 50 ug, Tag: GST $ 248.00
QP8370-ec-100ug Size: 100 ug, Tag: GST $ 428.00
QP8370-ec-200ug Size: 200 ug, Tag: GST $ 708.00
QP8370-ec-500ug Size: 500 ug, Tag: GST $ 1,228.00
QP8370-ec-1mg Size: 1 mg, Tag: GST $ 1,938.00
Shipping Information
On Demand Protein: 3-5 Week Lead Time. (Why?)
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QP8370-ec-10ug
Recombinant Human Rho guanine nucleotide exchange factor 7 Protein (179-428aa) General Information
Alternate Names
COOL1; Nbla10314; BETA-PIX; COOL-1; PAK3; P50BP; PIXB; P85; P85COOL1; P50; P85SPR
Curated Database and Bioinformatic Data
Gene SymbolARHGEF7
Entrez Gene ID8874
Ensemble Gene IDENSG00000102606
RefSeq Protein Accession(s)NP_001106983.1
RefSeq mRNA Accession(s)NM_001113511.2, NM_001113512.2, NM_001113513.1, NM_001320851.1, NM_001320853.1, NM_001320854.1, NM_001330597.1, NM_001330598.1, NM_003899.3, NM_145735.3, XM_017020824.1, XM_017020825.1
UniProt ID(s)Q14155
UniGene ID(s)Hs.508738
HGNC ID(s)HGNC:15607
COSMIC ID Link(s)ARHGEF7
KEGG Gene ID(s)hsa:8874
PharmGKB ID(s)PA24977
General Description of Recombinant Human Rho guanine nucleotide exchange factor 7 Protein (179-428aa).
Acts as a RAC1 guanine nucleotide exchange factor (GEF) and can induce mbrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions . May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.3 Publications

Human Rho guanine nucleotide exchange factor 7 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant Rho guanine nucleotide exchange factor 7 based upon sequence from: Human
Host: QP8370 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Rho guanine nucleotide exchange factor 7, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8370.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met179 - His428
Amino Acid Sequence: MTDNSNNQLV VRAKFNFQQT NEDELSFSKG DVIHVTRVEE GGWWEGTLNG RTGWFPSNYV REVKASEKPV SPKSGTLKSP PKGFDTTAIN KSYYNVVLQN ILETENEYSK ELQTVLSTYL RPLQTSEKLS SANISYLMGN LEEICSFQQM LVQSLEECTK LPEAQQRVGG CFLNLMPQMK TLYLTYCANH PSAVNVLTEH SEELGEFMET KGASSPGILV LTTGLSKPFM RLDKYPTLLK ELERHMEDYH
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Rho guanine nucleotide exchange factor 7 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human Rho guanine nucleotide exchange factor 7 Protein