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Recombinant Human HMGB1 / HMG1 Protein

$ 79.00$ 3,488.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP8377
Species: Human
Available Tags: GST
Host: E. coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids): 172

Size
Tag Clear selection
Shipping Information
4-6 weeks
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP8377-ec-10ug
Recombinant Human HMGB1 / HMG1 Protein General Information
Alternate Names
HMGB1; HMG1; HMG3; SBP-1; HMG-1; HMG1
Curated Database and Bioinformatic Data
Gene SymbolHMGB1
Entrez Gene ID3146
Ensemble Gene IDENSG00000189403
RefSeq Protein Accession(s)NP_001300821.1
RefSeq mRNA Accession(s)NM_001313892.1, NM_001313893.1, NM_002128.5
UniProt ID(s)P09429
UniGene ID(s)Hs.434102
HGNC ID(s)HGNC:4983
COSMIC ID Link(s)HMGB1
KEGG Gene ID(s)hsa:3146
PharmGKB ID(s)PA188
General Description of Recombinant Human HMGB1 / HMG1 Protein.
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type Cytoplasmic domain processes in developing cells .

Human HMGB1 / HMG1 Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant HMGB1 / HMG1 based upon sequence from: Human
Host: QP8377 protein expressed in E. coli (GST-tag) or Hi5 cells (His-tag).
Tag: GST or His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) HMGB1 / HMG1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8377.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Lys8 - Glu179
Amino Acid Sequence: KPRGKMSSYA FFVQTCREEH KKKHPDASVN FSEFSKKCSE RWKTMSAKEK GKFEDMAKAD KARYEREMKT YIPPKGETKK KFKDPNAPKR PPSAFFLFCS EYRPKIKGEH PGLSIGDVAK KLGEMWNNTA ADDKQPYEKK AAKLKEKYEK DIAAYRAKGK PDAAKKGVVK AE
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human HMGB1 / HMG1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.

Limitations and Performance Guarantee

This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human HMGB1 / HMG1 Protein